Results 71 to 80 of about 10,906,711 (291)
Decrypting cancer's spatial code: from single cells to tissue niches
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik+4 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini+2 more
wiley +1 more source
Health Benefits, Risks, and Cost-Effectiveness of Influenza Vaccination of Children
We estimated cost-effectiveness of annually vaccinating children not at high risk with inactivated influenza vaccine (IIV) to range from US $12,000 per quality-adjusted life year (QALY) saved for children ages 6–23 months to $119,000 per QALY saved for ...
Lisa A. Prosser+9 more
doaj +1 more source
[Excerpt] America needs a raise, in the worst kind of way. While productivity, profits, executive pay and the stock market keep going up, working family incomes keep going down, widening the gap between the rich and the rest of us and creating a ...
AFL-CIO Department of Economic Research
core +1 more source
ABSTRACT Objective To compare the effectiveness of high‐efficacy treatments (HET) and low‐efficacy treatments (LET) in NMOSD patients with anti‐aquaporin‐4 antibodies (AQP4‐ab). Methods In this multi‐center study, we analyzed 183 AQP4‐ab seropositive NMOSD patients who received immunosuppressive treatments (IST).
Xiang Li+10 more
wiley +1 more source
ABSTRACT Purpose This study aimed to explore the association between quantitative shape irregularity and density heterogeneity of hematomas and hematoma expansion (HE) for intracerebral hemorrhage (ICH) patients. Methods This cohort study included patients arriving within 24 h of symptom onset between August 2021 and July 2022 as the derivation cohort ...
Zeqiang Ji+11 more
wiley +1 more source
The economic viability of on-road wireless charging of electric vehicles (EVs) strongly depends on the choice of the inductive power transfer (IPT) system configuration (static or dynamic charging), charging power level and the percentage of road ...
Aditya Shekhar+3 more
doaj +1 more source
Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features
ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó+17 more
wiley +1 more source
Using Exergy to Correlate Energy Research Investments and Efficiencies: Concept and Case Studies
The use of exergy to correlate energy-utilization efficiencies and energy research investments is described. Specifically, energy and exergy losses are compared with energy research and development expenditures, demonstrating that the latter correlates ...
Marc A. Rosen
doaj +1 more source