Results 111 to 120 of about 525,332 (310)

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai, Sen Zhang, Haipei Zhang, Yating Zhang, Junhong Guo, Xiaoyan Yang   +5 more
wiley   +1 more source

Economic Burden of Treatment-Resistant Depression

Journal of Pharmacoeconomics and Pharmaceutical Management
Background: Treatment-resistant depression (TRD) is a highly prevalent condition and is generally referred to as the failure of at least two or more prior treatments with antidepressants or augmentation therapy with adequate dose and duration.
Swati Sucharita Dash, Merlin Roshma Sherin, Jignesh Bhate, Guruprasad KS Rao   +3 more
doaj  

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

ECONOMIC BURDEN OF HYPERCHOLESTEROLEMIA IN THE RUSSIAN FEDERATION

Рациональная фармакотерапия в кардиологии, 2018
Background. The prevalence of hypercholesterolemia (HCE) is quite high in the Russian Federation (RF), and it is associated with clinical consequences and with potential economic impact.
A. V. Kontsevaya, Yu. A. Balanova, A. E. Imaeva, M. B. Khudyakov, O. I. Karpov, O. M. Drapkina   +5 more
doaj   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source

Economic burden of refractory chronic spontaneous urticaria on Kuwait's health system [PDF]

, 2016
Mona Al-Ahmad,1 Maryam S Alowayesh,2 Norman V Carroll31Microbiology Department, Faculty of Medicine, 2Pharmacy Practice Department, Faculty of Pharmacy, Kuwait University, Kuwait; 3Division of Pharmacoeconomics and Health Outcomes, School of Pharmacy ...
Al-Ahmad M, Carroll NV, Alowayesh MS
core   +1 more source

The economic burden of psoriatic diseases in Taiwan [PDF]

, 2017
Background: Psoriasis is associated with significant economic burdens. Data regarding costs for psoriasis patients in Taiwan are not available. Objective: To estimate the economic burden of psoriasis in Taiwan.
蔡呈芳, Chen, Kuan-Chen;Hung, Sheng-Tzu;Yang, Ching-Wen Wendy;Tsai, Tsen-Fang;Tang, Chao-Hsiun   +1 more
core   +1 more source

The economic burden of hemolysis [PDF]

Clinical Chemistry and Laboratory Medicine (CCLM), 2015
Janne, Cadamuro, Helmut, Wiedemann, Cornelia, Mrazek, Thomas Klaus, Felder, Hannes, Oberkofler, Georg Martin, Fiedler, Elisabeth, Haschke-Becher   +6 more
openaire   +2 more sources

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik   +5 more
wiley   +1 more source