Results 211 to 220 of about 1,785,005 (312)

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan   +12 more
wiley   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

open access: yesAdvanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec   +5 more
wiley   +1 more source

Economic burden of malaria in children under the age of five in Burundi. [PDF]

open access: yesMalar J
Niyibitegeka F   +5 more
europepmc   +1 more source

High‐Performance Electrocatalysts of Potassium Lactate Oxidation for Hydrogen and Solid Potassium Acetate Production

open access: yesAdvanced Materials, Volume 37, Issue 13, April 2, 2025.
Potassium lactate, produced from polylactic acid plastic waste, is oxidized to potassium acetate on an anode using Ni(Co)OOH as the electrocatalyst, while hydrogen is simultaneously generated at the cathode, through a highly efficient industrial‐scale electrolysis system.
Jun Hu   +9 more
wiley   +1 more source

Investigating the health economic burden of atopic disease in children from the EAT-On Study. [PDF]

open access: yesPediatr Allergy Immunol
Foong RX   +6 more
europepmc   +1 more source

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

open access: yesAdvanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen   +5 more
wiley   +1 more source

Societal Economic Burden of Antibiotic Resistance in Uganda: A Cost of Illness Study. [PDF]

open access: yesPharmacoecon Open
Nuwamanya E   +17 more
europepmc   +1 more source

Engineered Protein‐Based Ionic Conductors for Sustainable Energy Storage Applications

open access: yesAdvanced Materials, EarlyView.
Rational incorporation of charged residues into an engineered, self‐assembling protein scaffold yields solid‐state protein films with outstanding ionic conductivity. Salt‐doping further enhances conductivity, an effect amplified in the engineered variants. These properties enable the material integration into an efficient supercapacitor.
Juan David Cortés‐Ossa   +14 more
wiley   +1 more source

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