Results 61 to 70 of about 116,677 (304)
Economic Fluctuations in Russia (from the late 1920s to 2015)
Russian Journal of Economics, 2015 In many respects, the historical trajectory of the Russian economy during the XX century has been a terra incognita until now. As for official statistics, at least three important reasons can be given for this. First, many relevant indicators were either
Sergey Smirnov
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Economic crises and mortality: a review of the literature
International Journal of Clinical Practice, 2009 Studies evaluating the association of economic variables with mortality have produced mixed findings.We sought to evaluate whether economic crises confer increase in mortality.We reviewed studies analysing mortality in the general population in periods of economic crisis compared with periods prior to or after the crisis, by searching PubMed, Scopus ...
Falagas, M.E. +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Causative Relationships between Economic and Financial Crises [PDF]
, 2009 The current crisis is viewed by most analysts as a financial one, generated by malfunctioning financial market rules affecting the real economy through wealth effects, rising uncertainty and credit crunch. This interpretation is certainly consistent with
SCARANO, Giovanni
core
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
OVERVIEW: ECONOMIC CRISES AND HUMAN DEVELOPMENT
Estudios Económicos, 2010 Examinamos el efecto de choques económicos pasados sobre indicadores de desarrollo humano a fin de comprender mejor el impacto potencial de la crisis económica mundial actual.
Pedro Conceição +2 more
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