Results 201 to 210 of about 287,754 (265)

Farmers' perception of termite infestation, economic importance, and control practices in Dodota district, Southeast Ethiopia. [PDF]

J Ethnobiol Ethnomed
Taddese S, Asaye Y, Muhammed A.
europepmc   +1 more source

Impaired Chaperone‐Mediated Autophagy Accelerates Intervertebral Disc Degeneration by Inducing MIDN Accumulation to Target TSC2 for Proteasomal Degradation

Advanced Science, EarlyView.
This graphical abstract illustrates how chaperone‐mediated autophagy (CMA) regulates intervertebral disc degeneration (IDD). Under normal homeostasis (B), CMA degrades cytoplasmic Midnolin (MIDN) to maintain proteostasis. Under inflammatory stress (A), impaired CMA leads to cytoplasmic MIDN accumulation.
Xianglong Chen, Haiyang Gao, Wang Wu, Pengzhi Shi, Yuhang Chen, Anran Zhang, Zhangrong Cheng, Wenbo Wu, Zimu Yu, Yukun Zhang   +9 more
wiley   +1 more source

Four decades of intensifying Southern Ocean swells along the Pacific coast of the Americas. [PDF]

Nat Commun
Lobeto H, Menendez M, Semedo A, Losada IJ, Lemos G.   +4 more
europepmc   +1 more source

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

Advanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin, Zhike Xie, Danyue Zhao, Lin Yang, Yiqun Wan, Zuwei Liu, Situ Xiong, Ying Zhang, Lei Feng, Hao Wan   +9 more
wiley   +1 more source

Small sips, big losses: measuring the feeding threshold of Lygus (Hemiptera: Miridae) on faba bean (Vicia faba) seeds. [PDF]

J Econ Entomol
Aguiar-Cordero T, Prager SM.
europepmc   +1 more source

A BSCB‐Penetrating Nanoplatform for Enhanced Luteolin Delivery in PRMT2‐Targeted Epigenetic Therapy of Spinal Cord Injury

Advanced Science, EarlyView.
In this work, MSN‐BO@LUT penetrates the blood‐spinal cord barrier for luteolin delivery in spinal cord injury. The nanodrug suppresses neuroinflammation and promotes functional recovery of the spinal cord. Mechanistically, luteolin targets protein arginine N‐methyltransferase (PRMT2) to decrease toll‐like receptor 4 (TLR4) methylation, thereby ...
Yixuan Wang, Bo Jin, Shipian Li, Qianxi Ouyang, Yu Xiao, Jiaxin Wen, Yehua Lai, Ping Wang, Yongjun Wang, Xuejun Cui, Weian Zhang, Min Yao   +11 more
wiley   +1 more source

Robust Solar Radiation Modification Strategy for Achieving Temperature Targets. [PDF]

Risk Anal
Zheng GL, Wu JY, Zhang T, Liao H.
europepmc   +1 more source

Ion‐Exchange‐Driven Ternary Organic Neuromorphic Devices with High Efficiency and Stability

Advanced Science, EarlyView.
Spontaneous ion exchange in a ternary polymer–ionic liquid blend disrupts the phase‐separated ionic domains of the binary film and creates a more homogeneous polymer–ion environment. This ionically reorganized matrix enables stable and efficient electrochemical doping, leading to ion‐gel‐gated organic electrochemical transistors with enhanced ...
Sungmin Lee, Vivek Pratap Singh, Hyeonryul Lee, Young‐Yong Kim, Yong‐Ryun Jo, Changhoon Lee, Ji Hoon Shim, Namsoo Lim, Guanjie Wang, Junyeong Sung, Dongyeop Yang, Zhongwu Wang, Liqiang Li, Chandran Balamurugan, Sooncheol Kwon   +14 more
wiley   +1 more source

Hydrological disasters and health losses: an index-based analysis for Brazil. [PDF]

Rev Saude Publica
Pereira GP, Sousa Filho JF, Ferreira TR, Costa PVMD, Ferreira AJF, Pescarini JM, Guimarães JMN, Velasco SRM, Neves DJD, Reis JSD, Silva KCMD, Santos GFD, Silva RCR, Andrade RFS, Barreto ML.   +14 more
europepmc   +1 more source