Results 41 to 50 of about 43,297,088 (300)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

The economic and social benefits of increasing Indigenous employment [PDF]

open access: yes, 2014
Using the latest available data and research, this paper provides estimates of the likely economic and social benefits of increasing Indigenous employment to the same level as in the non-Indigenous population.
Nicholas Biddle   +5 more
core  

BITCOIN’S WEEKLY CLOSING PRICE FORECASTING MODEL

open access: yesФінансово-кредитна діяльність: проблеми теорії та практики
The primary objective of this article is to provide a methodological approach to forecasting Bitcoin's weekly closing price, utilizing a correlation-indicator model.
Larysa Dokiienko, Andriy Ignatenko
doaj   +1 more source

Examining the Relationship Among Economic Growth, Exports and Total Productivity for OECD Countries Using Data Envelopment Analysis and Panel Data Analyses [PDF]

open access: yesMontenegrin Journal of Economics, 2017
The main objective of this paper is to explore the relationship between Total Factor Productivity (TFP) and economic growth and exports for OECD countries for the sample period 1990-2013.
İbrahim Hüseyni   +2 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

How does ICT capital stock affect high-quality economic growth? Evidence from China

open access: yesTechnological and Economic Development of Economy
As an essential driving force to promote industrial upgrading and technological innovation, ICT has gradually become the technological support for high-quality economic growth. This paper adopts the improved perpetual inventory method and entropy weight
Pengfei Guo, Zihua Hu, Xinyun Hu
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Investigating the role of good governance system in renewable energy transition in China and USA

open access: yesSustainable Futures
Governance system cannot be neglected in the fight against global warming. However, there is a significant gap in the literature on addressing how a good governance system can help facilitate a renewable energy transition, as previous studies are ...
Wenting Zhao   +3 more
doaj   +1 more source

Research on the economic analytical model of three-tier data factor market

open access: yes大数据, 2022
Although the establishment of the data factor market follows the general law of traditional marketoriented allocation of production factors, there still exists some unsolved problems such as unclear object of the transaction, imperfect pricing and ...
Zhipeng LU
doaj  

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