Results 51 to 60 of about 822,030 (316)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Platform Technology in Global Vaccine Regulation: Development, Applications, and Regulatory Strategies with Insights from China

Vaccines
The concept of “platform technology” gained prominence after the Ebola outbreak and since then has become essential to international vaccine (prophylactic vaccines against infectious disease) regulatory frameworks.
Xiaojing Li, Su Jin, Shuyang Guo, Dan Yang, Wenbo Sai, Xiao Qiu, Xin Zhao, Lan Wang, Tao Wang, Min Li   +9 more
doaj   +1 more source

Probabilistic cost-effectiveness analysis of controlled ovarian stimulation with recombinant FSH plus recombinant LH vs. human menopausal gonadotropin for women undergoing IVF

Reproductive Biology and Endocrinology, 2018
Background The association of recombinant FSH plus recombinant LH in 2:1 ratio may be used not only to induce ovulation in anovulatory women with hypogonadotropic hypogonadism but also to achieve multiple follicular developments in human IVF.
F. S. Mennini, A. Marcellusi, R. Viti, C. Bini, A. Carosso, A. Revelli, C. Benedetto   +6 more
doaj   +1 more source

The EU cohesion policy and economic development of Poland

, 2012
In order to remove regional economic disparities, the EU realizes the cohesion policy. The evaluation of the cohesion policy from the point of view of experiences of individual member states and the EU is not explicit.
Dorożyński, Tomasz
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Comparison of four value sets derived using different TTO and DCE approaches: application to the new region-specific PBM, AP-7D

Health and Quality of Life Outcomes
Background AP-7D is a newly developed preference-based measure (PBM) in East and Southeast Asia. However, no value set has been established yet. Comparison of the characteristics of value sets obtained by different methods is necessary to consider the ...
Takeru Shiroiwa, Tatsunori Murata, Yasuhiro Morii, Eri Hoshino, Takashi Fukuda   +4 more
doaj   +1 more source

Molecular and Functional Characterization of α Chain of Interleukin-15 Receptor (IL-15Rα) in Orange-Spotted Grouper (Epinephelus coioides) in Response to Vibrio harveyi Challenge

Animals, 2023
Interleukin-15 (IL15) is a proinflammatory cytokine that could induce the production of inflammatory cytokines. In this study, the α chain of the IL15 receptor of Epinephelus coioides (Ec-IL15Rα), a natural regulator of IL15, was identified, and immune ...
Yilin Zhang, Fan Wu, Guanjian Yang, Jichang Jian, Yishan Lu, Zhiwen Wang   +5 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Direct and indirect costs of cluster headache: a prospective analysis in a tertiary level headache centre

The Journal of Headache and Pain, 2020
Background Cluster headache (CH) is the most frequent trigemino-autonomic cephalgia. CH can manifest as episodic (ECH) or chronic cluster headache (CCH) causing significant burden of disease and requiring attack therapy and prophylactic treatment.
Andrea Negro, Paolo Sciattella, Valerio Spuntarelli, Paolo Martelletti, Francesco Saverio Mennini   +4 more
doaj   +1 more source

Economic Evaluation of Cochlear Implantation [PDF]

, 2000
Conference Theme: Challenges to specialists in the 21st ...
Au, D, Wong, BY, Hui, Y, Wei, W
openaire   +4 more sources