Results 51 to 60 of about 93,559 (265)

Economic Performance and Government Size [PDF]

open access: yesSSRN Electronic Journal, 2011
We construct a growth model with an explicit government role, where more government resources reduce the optimal level of private consumption and of output per worker. In the empirical analysis, for a panel of 108 countries from 1970-2008, we use different proxies for government size and institutional quality. Our results, consistent with the presented
Afonso, António, Jalles, João Tovar
openaire   +6 more sources

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Policy Coordination in the EU: Taking Stock of the Open Method of Coordination - Introduction

open access: yesEuropean Papers, 2018
(Series Information) European Papers - A Journal on Law and Integration, 2018 3(1), 203-205 | Article | (Abstract) This introduction presents the five Articles of this Special Section that was originally conceived at a workshop entitled "Taking Stock of ...
Evangelia Psychogiopoulou
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Enhanced Economic Governance in the EU: Alternative to a Political Union?

open access: yesInternational Journal of Management and Economics, 2014
In reaction to the sharp deterioration of fiscal positions and a sovereign debt crisis in the majority of EU member states, EU leaders have been strengthening the EU economic governance framework, in particular for the eurozone member states.
Kawecka-Wyrzykowska Elżbieta
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Control presupuestario en la Unión Europea, reforma constitucional, ajuste de los presupuestos de las Administraciones Públicas y su impacto en el autogobierno vasco en el marco del Concierto Económico

open access: yesRevista Vasca de Administración Pública, 2012
During the last two years, the European Union (EU) has adopted several instruments and mesures aimed at reinforcing the economic and budgetary coordination, especially among the Eurozone Member States.
Beatriz Pérez de las Heras   +1 more
doaj   +1 more source

THE EUROPEAN UNION’S GENERAL BUDGET- AN INSTRUMENT FOR ECONOMIC GOVERNANCE [PDF]

open access: yesCES Working Papers, 2015
The European Union is an unprecedented institution in the world, and therefore the general budget of the European Union is a specific budget, different from the national public budgets or the budgets of different organizations.
Tatiana COVALSCHI, Lilia ROTARU
doaj  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

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