Results 41 to 50 of about 716,648 (317)
Legal environment and corporate finance: evidence from the Italian manufacturing industry
Journal of Economic Structures, 2021 Considering the Italian manufacturing industry between 2014 and 2016 (more than 250,000 observations), this technical note analyzes the relation between the courts’ ability to enforce credit rights and the opportunity to finance business activities with ...
Greta Falavigna, Roberto Ippoliti
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Countervailing Conflicts of Interest in Delegation Games
Games, 2023 In this paper, we investigate optimal delegation mechanisms in the presence of countervailing conflicts of interest in the context of principal–agent problems.
Saori Chiba, Kaiwen Leong
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
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The Localization of Pharmaceutical Clinical Research in Europe [PDF]
Hospital Practices and Research, 2017 Background: Clinical research is a specific phase of the production process in the pharmaceutical industry in which companies test candidate drugs on patients in order to collect clinical evidence about safety and effectiveness.Objective: This paper is ...
Greta Falavigna, Roberto Ippoliti
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Model definitions to identify appropriate benchmarks in judiciary
Journal of Applied Economics, 2022 In this manuscript we present a comparative analysis of benchmarks based on technical efficiency scores computed using Data Envelopment Analysis with two different model specifications.
G. Falavigna, R. Ippoliti
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Economic Growth with Bubbles [PDF]
American Economic Review, 2010 We develop a stylized model of economic growth with bubbles in which changes in investor sentiment lead to the appearance and collapse of macroeconomic bubbles or pyramid schemes. These bubbles mitigate the effects of financial frictions. During bubbly episodes, unproductive investors demand bubbles while productive investors supply them.
Jaume Ventura, Alberto Martín
openaire +7 more sources
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Frontiers in NutritionIntroductionPreconception nutrition, the nutritional status of women before pregnancy, is crucial for maternal and child health. Interventions focusing on preconception nutrition can help break the intergenerational cycle of malnutrition by improving the
Abhishek Kumar +5 more
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