Results 51 to 60 of about 327,843 (264)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Partnership and competition: The strategic alliance between Schneider et Cie and the Škoda Works during the interwar period

Revista de Historia Industrial
Strategic alliances play an important role in business. This article analyses the interwar relationship between two major European arms manufacturing enterprises – the Czechoslovak Škoda Works and its post First World War majority shareholder the French ...
Aleš Skřivan, Tereza Burianová
doaj   +1 more source

The myth of the California of copper: the impact of the mining boom on the Huelva business fabric

Revista de Historia Industrial, 2019
In the mid 19th century, a select group of entrepreneurs attracted by the “mining boom”, with ties to European and Spanish trade networks, settled in the city of Huelva.
Juan Diego Pérez Cebada, Cinta Concepción García Vázquez   +1 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Structural changes, migrations and labour mobility in the Catalan cork sector in the early 20th century

Revista de Historia Industrial, 2019
Based on the information provided in the registers of inhabitants of Sant Feliu de Guíxols, Palafrugell and Palamós in 1930, the processes of emigration of workers from other towns are analysed.
Joaquim Alvarado Costa
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Oligopolistic agreements between the two main companies in a sector. The case of MZA and NORTE

Revista de Historia Industrial, 2019
The Spanish railway sector has been widely studied from various perspectives, due to the important role it has played in economic progress. This research focuses on a unique aspect, in the oligopolistic agreements reached by the two most important ...
Miguel Ángel Villacorta Hernández
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Economic History of Virginia in the Seventeenth Century. An in quiry into the material condition of the people based upon origi nal and contemporaneous records. By PHILTP ALEXANDER BRUCE. Two Vols. Pp. xix, 634, 647. Price, $6.00. London and New York: Macmillan & Co., I896 [PDF]

The ANNALS of the American Academy of Political and Social Science, 1896
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openaire   +2 more sources