Results 41 to 50 of about 7,366,666 (224)
Identification of Indicators’ Applicability to Settle Borrowers’ Probability of Default
Economics and Culture, 2016 Borrowers default risk is one of the most relevant types of risk in commercial banking and its assessment is important to secure business profitability and avoid huge losses during economic turbulences.
Jurevičienė Daiva, Rauličkis Darius
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
GLOBAL IMBALANCES, RISKS AND ECONOMIC SECURITY OF RUSSIA
Финансы: теория и практика, 2017 Article Retracted.This paper proposes an approach to the study of the impact of global imbalances and external economic risks for the Russian economy and its level of economic security.
V. K. Senchagov, A. I. Soloviev
doaj
Revista Brasileira de Engenharia Agrícola e Ambiental, 2022 Irrigation plays a fundamental role in advancing agricultural frontiers and increasing crop productivity, especially in semi-arid environments, because they exhibit high spatiotemporal rainfall variation. This practice is suggested even for adapted crops,
Thieres G. F. da Silva +8 more
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RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Nauka ta progres transportu, 2019 Purpose. The study aims at substantiating the method to determine the optimal volume of investments for improving basic economic indicators of the enterprise’s performance selected by the company management at random costs at each stage of its ...
Z. M. Gasanov
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Increase of Agribusiness in the Brazilian Amazon: Development or Inequality?
Earth, 2021 The growing global demand for soybean production combined with its increased market value could result in a new supercycle for this commodity. For Brazilian agribusiness, there has been an opportunity to increase exports, particularly in soybean ...
Rosana Cavalcante de Oliveira +1 more
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Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source