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Implications of Digitalization on the Persistence of Startups

open access: yesAdministrative Sciences
Digitalization is a transformative phenomenon catalyzing innovative paradigms and operational methodologies within the realm of business, with a pronounced impact on nascent enterprises, notably startups.
Débora De-Esteban-Escobar   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

المسئولية الجنائية للمؤسسات الاقتصادية في القانون العراقي والمقارن - دراسة مقارنة . [PDF]

open access: yesمجلة البحوث القانونية و الاقتصادية
احتل القانون الجزائي مكانة بارزة مع قيام الثورة الصناعية وظهور الآلات وما ألحقه ذلك من تطور في الميادين المختلفة من تجارية وصناعية وقيام العمران على أوسع صوره، إذ بدأت تظهر أنواع جديدة من الجرائم، كان ينبغي على المشرع التدخل للحد منها ووقف استمرارها ...
يونس حسن إسماعيل
doaj   +1 more source

Seasonality and food security among smallholder rural households in eastern Ethiopia: Evidence from panel data analysis

open access: yesCogent Economics & Finance, 2022
Food insecurity remains one of the major challenges in Ethiopia. There is scanty empirical evidence regarding the contribution of seasonality to household food and nutrition security. This study was conducted in eastern Ethiopia with the aim of examining
Chanyalew S. Aweke   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

ORGANIZAÇÃO ALFANDEGÁRIA E ESPAÇOS FISCAIS NO IMPÉRIO BRASILEIRO (1808-1836)

open access: yesAlmanack, 2019
RESUMO Este artigo tem como objetivo analisar a organização e funcionamento da estrutura administrativa das alfândegas brasileiras, tomando por base as transformações na arrecadação fiscal e a adequação do sistema alfandegário nas primeiras décadas do ...
Eduardo Silva Ramos
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Operational risk management, financial sector stability and sustainable development in West Africa

open access: yesDiscover Sustainability
Achieving sustainable development in West Africa is vital for integrating environmental, social and economic well-being in the region. This study examines the impact of operational risk management and financial sector’s stability on sustainable ...
Gabriel Osabohien   +3 more
doaj   +1 more source

Modelling Labour Productivity Under Industry 4.0: Digitalisation, Automation, and Firm Maturity

open access: yesMathematics
Firm-level productivity differentials in Industry 4.0 are increasingly linked to heterogeneous patterns of digital adoption. This study examines whether labour productivity among SMEs in Castilla-La Mancha is more strongly associated with effective ...
Sonia García-Moreno   +1 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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