Results 31 to 40 of about 3,643,016 (285)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Differences between male and female mortality in Colombia: a population-based analysis since 1980Research in context

open access: yesThe Lancet Regional Health. Americas
Summary: Background: Globally, women have consistently exhibited lower mortality and higher life expectancy than men. While this sex gap is well-documented in high-income countries, evidence from Latin America remains scarce. Colombia's history of armed
Oscar Espinosa   +3 more
doaj   +1 more source

A macro-distributive theory dispelling the econometric fog

open access: yesPSL Quarterly Review, 2013
The work presents a linear model of the private market sector of the economy built out of the main blocks of Keynes with some pieces furnished by Kalecki, Kaldor, and Robinson.
S. WEINTRAUB
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Mental health spending in Colombia: an analysis of rural and urban areas

open access: yesAnnals of General Psychiatry
Background Mental health expenditures are increasing worldwide. In developed countries there is evidence that increased health spending is associated with improved outcomes.
Oscar Espinosa   +5 more
doaj   +1 more source

The Looming USA-China Trade War and Its Consequences [PDF]

open access: yesGlobal Economic Observer, 2019
This paper looks at the evolution of the US-China economic relations from their complex, strong, multi-dimensional co-dependency, built up along many decades, to their growing disengagement and rivalry, following the lose-lose option for a trade war ...
SARMIZA PENCEA
doaj  

Risk assessments and structured care interventions for prevention of foot ulceration in diabetes: development and validation of a prognostic model

open access: yesHealth Technology Assessment, 2020
Background: Diabetes-related foot ulcers give rise to considerable morbidity, generate a high monetary cost for health and social care services and precede the majority of diabetes-related lower extremity amputations.
Fay Crawford   +15 more
doaj   +1 more source

Towards Economic Models for MOOC Pricing Strategy Design

open access: yes, 2017
MOOCs have brought unprecedented opportunities of making high-quality courses accessible to everybody. However, from the business point of view, MOOCs are often challenged for lacking of sustainable business models, and academic research for marketing ...
C Breidert   +4 more
core   +1 more source

New Monetarist Economics: Models [PDF]

open access: yes, 2010
The purpose of this paper is to discuss some of the models used in New Monetarist Economics, which is our label for a body of recent work on money, banking, payments systems, asset markets, and related topics. A key principle in New Monetarism is that solid microfoundations are critical for understanding monetary issues.
Williamson, Stephen D., Wright, Randall
openaire   +3 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

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