Results 31 to 40 of about 195,322 (264)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

An Analysis of the Copyright Protection of Works in Libraries: A Case Study of the National Library of Iran as the Authoritative Institution of Iranian Libraries [PDF]

open access: yesکتابداری و اطلاع‌رسانی
Objective: The present research was conducted with the aim of examining and analyzing the role of preservation of works in Iranian libraries, and specifically, the National Library of Iran as an authority among Iranian libraries.Methodology: The current ...
Zeinab Papi
doaj   +1 more source

Opportunities to tackle structural racism and ethnicity-based discrimination in recovering and rebuilding from the COVID-19 pandemic

open access: yesNature Communications, 2022
The impact of COVID-19 has been disproportionately felt by populations experiencing structural racial- and ethnicity-based discrimination. Here, the authors describe opportunities for COVID-19 response and recovery efforts to help build more equal and ...
Natalia Linos   +14 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

The Fictitious Liberal Divide

open access: yesErasmus Journal for Philosophy and Economics, 2017
The main question dividing classical and high liberals is about how economic rights rank compared to other rights and public goals. That is, the question is about what can or cannot outweigh such rights.
Åsbjørn Melkevik
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Wages, Talents, and Egalitarianism

open access: yesErasmus Journal for Philosophy and Economics, 2018
This paper compares Joseph Heath’s critique of the just deserts rationale for markets with an earlier critique due to Frank Knight, Milton Friedman, and Friedrich Hayek.
Andrew Lister
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

The effect of international energy prices on energy production in Sichuan, China

open access: yesEnergy Reports, 2020
Sichuan Province is China’s leading natural gas and hydropower producer. This article tests for the effects of international energy (nominal) prices on natural gas and hydropower production in Sichuan.
Gaolu Zou, Kwong Wing Chau
doaj   +1 more source

Privatization and Economic and Social Rights [PDF]

open access: yesHuman Rights Quarterly, 2018
Privatization is an ever more dominant model of economic and social rights (ESR) realization. Contracting out, public-private partnerships, and other approaches by which the private sector takes responsibility for, or supports the state in, delivering ESR-related goods and services are being advanced aggressively at both the national and supranational ...
openaire   +1 more source

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