Results 91 to 100 of about 30,851,546 (398)

High‐Efficacy Treatment in Neuromyelitis Optica Specturm Disorder Patients With Seropositive AQP4 Antibodies—A Real‐World Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To compare the effectiveness of high‐efficacy treatments (HET) and low‐efficacy treatments (LET) in NMOSD patients with anti‐aquaporin‐4 antibodies (AQP4‐ab). Methods In this multi‐center study, we analyzed 183 AQP4‐ab seropositive NMOSD patients who received immunosuppressive treatments (IST).
Xiang Li   +10 more
wiley   +1 more source

Information systems and economics

open access: yesCommunications of the ACM, 1998
Do big dollar expenditures on information systems pay off? Friction-free: is that what we really want markets to be? Is it time for consumers to say goodbye to fixed pricing? The Internet creates an environment in which the cost of buyer-seller interactions is cheaper than ever, and consumers can participate in the price-setting process—revealing ...
KAUFFMAN, Robert J.   +1 more
openaire   +3 more sources

Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó   +17 more
wiley   +1 more source

Economic incongruities in the European patent system [PDF]

open access: yes
Bruno van Pottelsberghe argues that the consequences of the fragmentation of the European patent system are more dramatic than the mere prohibitive costs of maintaining a patent in force in many jurisdictions.
Bruno van Pottelsberghe
core   +1 more source

Lithuanian financial system transformation in the context of globalization [PDF]

open access: yes, 2013
Purpose of the article: The purpose of the article is to discuss the transformation of the Lithuania finance system in the context of globalization. Exploring the interdependence between the financial system and the economy, in different periods. Analyze
Balkevicius, Arturas
core   +1 more source

The transformation of earth-system observations into information of socio-economic value in GEOSS [PDF]

open access: yes, 2005
The Group on Earth Observations System of Systems, GEOSS, is a co-ordinated initiative by many nations to address the needs for earth-system information expressed by the 2002 World Summit on Sustainable Development.
Ad De Roo   +41 more
core   +1 more source

Understanding Contributors of Resilience in Youth With Childhood‐Onset Systemic Lupus Erythematosus Through a Socioecological Lens: A Mixed‐Methods Study

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to identify themes contributing to resilience in childhood‐onset systemic lupus erythematosus (cSLE), distinguish between profiles of resilience, and examine how they relate to underlying themes and patient characteristics. Methods We conducted a mixed‐methods study of 21 patients with cSLE aged 11 to 19 years at a Canadian ...
Isabella Zaffino   +12 more
wiley   +1 more source

Modeling Commodity Flow as a Statistical Function of Lock Unavailability and Usage [PDF]

open access: yes, 2018
The inland waterway system in the United States allows for the transportation of commodities, and interruptions to the system can have remarkable economic consequences.
McGee, Grace
core   +2 more sources

Real‐World Cost‐Effectiveness of a Standardized Education and Exercise Therapy Program for Hip and Knee Osteoarthritis Compared to Usual Care

open access: yesArthritis Care &Research, EarlyView.
Objective We estimated the real‐world cost‐effectiveness of a standardized education and exercise therapy program (GLA:D) compared to usual care (UC) for people managing hip and/or knee osteoarthritis (HKOA). Methods We used a prospective matched cohort design to recruit people (aged >45 years) diagnosed with HKOA who used GLA:D or UC (not on a ...
Darren R. Mazzei   +4 more
wiley   +1 more source

MINNESOTA ENERGY-ECONOMIC INFORMATION SYSTEM [PDF]

open access: yes
The energy-economic impact forecasting system presented here is a modular approach to both economic modeling and information systems development. A set of eleven modules--market, investment, demand, production, (input-output), employment, value added ...
Maki, Wilbur R.   +2 more
core   +1 more source

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