Results 51 to 60 of about 24,381,306 (309)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Complex-Network-Guided High-Risk Substation Identification and Targeted Mitigation of Transformer DC Bias in Multi-Infeed UHVDC Receiving-End Grids

open access: yesEnergies
In multi-infeed UHVDC receiving-end grids, transformer DC-bias risk is affected not only by the magnitude of grounding-electrode current, but also by the AC-grid topology, substation grounding condition, voltage-level-dependent current limits, and ...
Jingbo Song   +8 more
doaj   +1 more source

The Economic Philosophy of Micro-Credit System [PDF]

open access: yes, 2016
. This paper aims at locating the practice of micro-credit system into a larger theoretical canvas of economic theory and philosophy. A systems theoretic approach has been adopted. Emergence of the ‘excluded’ class has been explained with the help of the
MISHRA, Sudhanshu K.; Avantika, Rohini Sector-1 Delhi – 110085 Retd. Professor, Dept. of economics North-Eastern Hill University, Shillong (India): 91 - 793022
core   +1 more source

RANDOM DYNAMICAL SYSTEMS IN ECONOMICS [PDF]

open access: yesStochastics and Dynamics, 2001
This paper surveys recent advances in the application of random dynamical systems theory in economics. It illustrates the usefulness of this framework for modeling and analysis of economic phenomena with stochastic components, mainly focusing on stochastic dynamic models of economic growth.
openaire   +5 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

DYNAMIC DEVELOPMENT OF THE RESIDENTIAL REAL ESTATE MARKET IN MOSCOW

open access: yesНаука Красноярья
Moscow occupies a special place in the real estate market of the Russian Federation, as it is characterized by a large volume of new residential real estate, the existence of large market players and the presence of high (compared with other regions of ...
Yulia A. Milkina, Ekaterina E. Makarova
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

National Security and Coronavirus Disease (COVID-19) Pandemic: Challenges to the Economic System of the State and Prospects for Ensuring its Security

open access: yesРегионология, 2020
Introduction. The current transformation of economic relations in the society caused by coronavirus disease (COVID-19) pandemic poses a threat to national security of all countries.
Natalia S. Bezuglaya, Inna N. Shamray
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Directions of ecological business development in the regional economic system [PDF]

open access: yesBIO Web of Conferences
Today, the development of ecological entrepreneurship is a demand of the times, and it depends on the production potential of the regions. The most important aspect of the regions is its economic system, which focuses on the ecological aspects of the ...
Rakhimov Tukhtabek   +4 more
doaj   +1 more source

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