Results 31 to 40 of about 12,243,142 (300)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

EVA: Economic Value Added

open access: yesCiencia UNEMI, 2011
It is important to know all the techniques and tools that allow us to be aware of the evolution of our company, the results of the management steps carried out by the whole personnel, to see if the efforts and changes that are made affect or don´t affect
Armendáriz-Lasso, Enrique
doaj  

Pengaruh Leverage Profitabilitas dan Economic Value Added Terhadap Nilai Perusahaan Pertambangan di Bursa Efek Indonesia

open access: yesJ-MKLI (Jurnal Manajemen dan Kearifan Lokal Indonesia), 2019
Firm value used as a measure of the success of the company's management in the future prospects of operations so that it can realize the trust of the company's shareholders and also investors.
Ni Ketut Ping Purnamasari   +1 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Intellectual Capital Measurement and Evaluation Models Based on Assets Return as Non-Accounting Value [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2022
In recent decades, the emphasis on the knowledge resources and organizational skills of companies has contributed to the creation of a broad understanding of the strategic role of intangible resources for the success of a company, resources consisting ...
Cati-Loredana Dumitru (Soare)
doaj  

The Effect of Information Content of Economic Value-Added and Traditional Criteria on Firms’ Markets Value Added [PDF]

open access: yesبررسی‌های حسابداری و حسابرسی, 2013
Performance evaluation is a process which helps shareholders to make decisions of optimal investment. So the present study investigates the economic value added of relative and additive information content toward traditional criteria, shareholder salary ...
Asadi Asadi   +2 more
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Better off Dead: “Value Added” in Economic Policy Debates [PDF]

open access: yesThe School of Public Policy Publications, 2015
Politicians across Canada have come to understand that our economy improves when we develop so-called “value added” industries and jobs. They suppose that turning raw materials into finished goods creates more value added than simply extracting and ...
Trevor Tombe
doaj   +2 more sources

Penerapan Economic Value Added untuk Memaksimalkan Nilai Perusahaan: Studi Kasus PT XYZ

open access: yesJournal the Winners, 2004
EVA is an indicator about the value creation from an investation. Positive EVA indicate that a company is sucess in creating added value for share holders. That sincronize with the purpose to maximize the company value.
Hartiwi Prabowo
doaj   +1 more source

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