Results 41 to 50 of about 2,851,619 (330)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

open access: yesFEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law   +6 more
wiley   +1 more source

Why Economic Theories and Policies Fail? Unnoticed Variables and Overlooked Economics [PDF]

open access: yesarXiv, 2022
Accuracy of economic theories and efficiency of economic policy strictly depend on the choice of the economic variables and processes mostly liable for description of economic reality. That states the general problem of assessment of any possible economic variables and processes chargeable for economic evolution.
arxiv  

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

open access: yesFEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang   +7 more
wiley   +1 more source

FILSAFAT EKONOMI ADAM SMITH

open access: yesJurnal Filsafat, 2016
This essay wants to describe and analyze Adam Smith’s philosophy of Economic. Adam Smith, as the Father of Economics, has really attempted to make economics as a positive-empirical science.
Cuk Ananta Wijaya
doaj   +1 more source

Is Economics an Empirical Science? If not, can it become one?

open access: yesFrontiers in Applied Mathematics and Statistics, 2015
Today’s mainstream economics, embodied in Dynamic Stochastic General Equilibrium (DSGE) models, cannot be considered an empirical science in the modern sense of the term: it is not based on empirical data, is not descriptive of the real-world economy ...
Sergio Mario Focardi   +1 more
doaj   +1 more source

The Impact of Services on Economic Complexity: Service Sophistication as Route for Economic Growth [PDF]

open access: yesPLoS ONE 11(8) 2016, 2016
Economic complexity reflects the amount of knowledge that is embedded in the productive structure of an economy. By combining tools from network science and econometrics, a robust and stable relationship between a country's productive structure and its economic growth has been established.
arxiv   +1 more source

TEORI EKONOMI MAKRO DALAM LITERATUR ISLAM KLASIK

open access: yesAn-Nisbah: Jurnal Ekonomi Syariah, 2020
Islamic economics is a science that was born as an alternative to conventional economics, Schumpeter wrote down the economic history of Greek philosophers and immediately made a long leap for 500 years known as the great gap.
Nirmala Baini, Fitri Rahmawati
doaj   +1 more source

Economic Design of Memory-Type Control Charts: The Fallacy of the Formula Proposed by Lorenzen and Vance (1986) [PDF]

open access: yesAhmadi-Javid, A., & Ebadi, M. (2020). Economic design of memory-type control charts: The fallacy of the formula proposed by Lorenzen and Vance (1986). Computational Statistics, DOI: 10.1007/s00180-020-01019-6, 2017
The memory-type control charts, such as EWMA and CUSUM, are powerful tools for detecting small quality changes in univariate and multivariate processes. Many papers on economic design of these control charts use the formula proposed by Lorenzen and Vance (1986) [Lorenzen, T. J., & Vance, L. C. (1986).
arxiv   +1 more source

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