Results 61 to 70 of about 6,251,236 (415)

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

On the minimal simplex economy [PDF]

open access: yesarXiv, 2023
In our previous paper we proved that every affine economy has a competitive equilibrium. We define a simplex economy as an affine economy consisting of a stochastic allocation (defining the initial endowments) and a variation with repetition of the number of commodities taking the number of consumers (representing the preferences).
arxiv  

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

Uma introdução ao capitalismo dirigido pelas finanças

open access: yesNovos Estudos CEBRAP, 2008
O capitalismo dirigido pelas finanças sempre teve uma propensão a crises financeiras em momentos fundamentais de sua expansão territorial ao trazer economias até então dirigidas pelo Estado para a órbita da regulamentação do mercado.
Robert Guttmann
doaj   +1 more source

Innovation and the circular economy: A systematic literature review

open access: yesBusiness Strategy and the Environment, 2021
The circular economy emerged as an alternative model to the linear system, which now appears to be reaching its physical limitations. To transition to a circular economy, companies must not only be aware of but also engage in more sustainable practices ...
Nathalia Suchek   +4 more
semanticscholar   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Economy and Climate Change The Paris Conference - December 2015 [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2016
The Paris Agreement on climate change issues was adopted at the COP.21 of December12, 2015. Representatives from 195 countries have agreed to undertake concrete measuresin order to contain the rise of global atmospheric temperatures until the end of the ...
Viorel Pop
doaj  

Mathematical modeling applied to the growth of tilapia in net cages in the sub middle of the São Francisco river [PDF]

open access: yesEngenharia Agrícola, 2014
This study aimed to apply mathematical models to the growth of Nile tilapia (Oreochromis niloticus) reared in net cages in the lower São Francisco basin and choose the model(s) that best represents the conditions of rearing for the region.
José de A. de Sousa Júnior   +4 more
doaj   +2 more sources

Product design and business model strategies for a circular economy

open access: yes, 2016
The transition within business from a linear to a circular economy brings with it a range of practical challenges for companies. The following question is addressed: What are the product design and business model strategies for companies that want to ...
N. Bocken   +3 more
semanticscholar   +1 more source

China Confronts the Challenge of Globalization: Implications for Domestic Cohesion and International Cooperation [PDF]

open access: yes, 1998
Examines how the globalization process will affect Chinese leaders' interest in participating in international efforts to respond to global challenges, and the Chinese leadership's capacity to address domestic and international ...
Elizabeth Economy
core  

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