Results 61 to 70 of about 2,468,844 (307)
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Revista Justicia y Derecho, 2023 The regulatory state is inescapable in liberal democracies and republics around the world. With similar ubiquity, it is criticized in various ways: for growing without limits, not meeting its objectives and benefiting certain groups to the detriment of ...
Oscar Sumar Albujar, Rodrigo Hawkins
doaj +1 more source
Determinants of the Informal Economy in MENA Economies
Eskişehir Osmangazi Üniversitesi Sosyal Bilimler Dergisi, 2018 Using data from a panel of 23 Middle East and North African (MENA) economies over the years between 1999-2015, this paper examines the determinants of the shadow economy in this region. Specifically, we reexamine the economic and social variables used in the cross-country empirical literature on the shadow economy and compare them with those of the ...
ATEŞAĞAOĞLU, Orhan Erem +2 more
openaire +3 more sources
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
The Impact of Economic Change on Livelihood Spaces (Agriculture and Animal Husbandry); Qazvin Rural Housing [PDF]
مسکن و محیط روستا, 2020 Rural housing is the most primitive and original form of housing for people with fixed habitation. It has developed and expanded due to the changes in the forms of nomadism, especially those that occurred based on agriculture and animal husbandry. of the
Zahra Beigom Taghavi +2 more
doaj
Navigating the Global Economy: A Comprehensive Analysis of the Massachusetts Maritime Economy [PDF]
, 2017 The Massachusetts Maritime Economy is comprised of 5,555 establishments that employ 90,482 workers, pay $3.4 billion in total wages, and account for $6.4 billion in gross state product. These businesses are a significant economic driver in Massachusetts,
Stickles, Holly +8 more
core
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
The New Blue Economy: the Future of Sustainability [PDF]
, 2016 The world’s ocean is the world’s life support. Many human activities have defined a negative relationship with the ocean. Simply put: we dump too much bad stuff in, and we take too much good stuff out.
Mark J Spalding, Spalding, Mark J
core +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Understanding the Ocean Economy within Regional and National Contexts [PDF]
, 2013 Extending discussion of the ocean economy beyond “How Big” – Changes in the U.S. related to the Great Recession – Decomposing changes to major types of change – Finding relative sizes Exploring the expanding attention to the ocean economy in ...
Kildow, Judith T., Dr, Colgan, Charles S
core +1 more source