Results 181 to 190 of about 562,611 (249)

Spatio-temporal patterns and driving mechanisms of ecosystem services in mountainous regions: A multi-scale analysis of the Yanshan-Taihang mountain area. [PDF]

Sci Rep
Che J, Zhu X, Niu X.
europepmc   +1 more source

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

Advanced Science, EarlyView.
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel, Anna Meurer, Badeel Kh. Q. Zaghla, Bilge Atay, Daniel Steiert, Luca V. Hummel, Konstandina Isaakidis, Chuanbing Zang, Michael Korenkov, Marlon Schielin, Schayan Yousefian, Shima Mecklenbräuker, Marieluise Kirchner, Simon Haas, Antonia Busse, Philipp Mertins, Stefan Müller, Matthias Wirth, Martin G. Klatt, Ulrich Keller   +19 more
wiley   +1 more source

Vegetation C: N: P stoichiometry and ecosystem carbon storage under different grazing patterns on the Tibetan Plateau. [PDF]

Front Plant Sci
He G, Liu X, Li Y, Ji T.
europepmc   +1 more source

Assessing the priorities of stakeholders regarding forest ecosystem services in Japan [PDF]

Akira Mori, K. Suzuki, Masashi Soga, Tetsuji Ota, Masumi Hisano, Yohei Arata, Kahoko Tochigi, Kazuhiro Kawamura, Makoto Ehara, Wataru Hotta, Kosuke Nakama, Takanobu Aikawa, Rei Shibata, Fumiko Nakao, Yosuke Kuramoto, M Hirose, Kentaro Sano, Rebecca Spake, Nobuya Mizoue   +18 more
openalex   +1 more source

Novel Antifungal Scaffold Targeting Tubulin Overcomes Sclerotinia Sclerotiorum Resistance

Advanced Science, EarlyView.
Addressing pesticide resistance, novel chromone‐acylhydrazone hybrids targeting fungal tubulin are synthesized. Compound G24 potently inhibited S. sclerotiorum (EC50 = 0.21µg mL−1) and demonstrated enhanced field performance via microencapsulation, offering a sustainable strategy against resistance and for global food security.
Lihui Shao, Xianqun Hu, Ying Wu, Xiang Zhou, Bo Zhang, Song Yang   +5 more
wiley   +1 more source

Editorial: Ecosystem and planetary health and emerging/re-emerging zoonoses. [PDF]

Front Vet Sci
Areda D, Edao B.
europepmc   +1 more source

Research on the Driving Factors and Trade-Offs/Synergies of Woodland Ecosystem Services in Zhangjiajie City, China [PDF]

Shuangfei Zhao, Wei Zeng, Qian Yang, Rong Zheng   +3 more
openalex   +1 more source

Entrepreneurial Cultural Affinity Spaces (ECAS): Design of Inclusive Local Learning Ecosystems for Social Change, Innovation and Entrepreneurship

, 2020
Stefania Savva, Nicos Souleles, Ana Margarida Ferreira   +2 more
openalex   +2 more sources

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source

A fundamental trade-off among resilience, resistance, efficiency, and redundancy in tidal wetlands. [PDF]

Ecology
Lerner JE, Feagin RA, Huff TP, Najjar RG, Layton A, Herrmann M, Fuentes JD.   +6 more
europepmc   +1 more source