Results 221 to 230 of about 562,611 (249)

Microcystin‐LR Triggers Renal Tubular Ferroptosis Through Epigenetic Repression of GPX4: Implications for Environmental Nephrotoxicity

Advanced Science, EarlyView.
MC‐LR stabilizes DNMT1/3a by blocking their ubiquitin‐mediated degradation, leading to Gpx4 promoter hypermethylation and E2F4/NCoR‐associated transcriptional repression, which drives renal tubular ferroptosis in mice. Pharmacological inhibition of DNA methylation (SGI‐1027) or ferroptosis (Fer‐1) disrupts this DNMT‐GPX4 axis, thereby alleviating MC‐LR‐
Shaoru Zhang, Qi Gao, Yi Peng, Huan Zhang, Qi Shen, Meihong Guo, Yuqing Gong, Lei Chu, Weidong Wu, Yanting Wen, Wangsen Cao, Yong Wang, Lihui Wang   +12 more
wiley   +1 more source

Riparian Forests and Macroinvertebrates Support Multiple Ecosystem Processes Across Temperate and Tropical Streams. [PDF]

Ecosystems
Oester R, de Omena PM, da Costa LC, Moretti MS, Altermatt F, Bruder A.   +5 more
europepmc   +1 more source

Modelling ecosystem services – a tool for assessing novel ecosystems functioning in the urban-industrial landscape

Gabriela Woźniak, Wojciech Bryś, Roman Dychkovskyi, Artur Dyczko, Teresa Nowak, Anna Piekarska‐Stachowiak, Leszek Trząski, Tadeusz Molenda, Agnieszka Hutniczak   +8 more
openalex   +1 more source

Single‐Cell Profiling Across Immune Tissues and Organs Reveals Immunosenescence Signatures in Male Rhesus Monkeys

Advanced Science, EarlyView.
Single‐cell profiling across bone marrow, spleen, mesenteric lymph, and blood in rhesus monkeys reveals organ Immunosenescence. GZMB rises with age, particularly in cytotoxic and terminally exhausted CD8+ T cells, and BHLHE40 emerges as a key transcription factor enriched across multiple CD8+ subsets, regulating pro‐inflammatory and exhaustion‐related ...
Shengnan Wang, Zhengna Zhu, Hongju Yang, Yaping Yan, Luyao Ran, Naixue Yang, Yichao Wang, Li Wu, Bing Bai, Weizhi Ji, Wei Si   +10 more
wiley   +1 more source

From elastic thresholds to predictive management: Advancing freshwater ecosystem conservation. [PDF]

Environ Sci Ecotechnol
Xie H, Jin X, Zhan A, Zhao X, Jonson AC, Wu F.   +5 more
europepmc   +1 more source

scPER: A Rigorous Computational Approach to Determine Cellular Subtypes in Tumors Aligned With Cancer Phenotypes From Total RNA Sequencing

Advanced Science, EarlyView.
scPER presents an adversarial‐autoencoder framework that deconvolves bulk total RNA‐seq to quantify tumor‐microenvironment cell types and uncover phenotype‐linked subclusters. Across diverse benchmarks, scPER improves accuracy over existing tools.
Bingrui Li, Xiaobo Zhou, Raghu Kalluri
wiley   +1 more source

From Grave to Cradle: Kombucha Waste for Sustainable Electronics

Advanced Science, EarlyView.
This study introduces a sustainable method to purify kombucha bacterial cellulose (KBC) with sodium bicarbonate and hydrogen peroxide, avoiding harsh chemicals. KBC films are patterned with gold and function as pressure sensors for flatfoot gait detection. At the end‐of‐life, the KBC‐based device biodegrades in soil, leaving environmentally benign gold
Xin Ying Chan, Xiaolu Sun, Eddy Yi Ler Pang, Iris Zhiyu Ren, Xuan Zhang, Pengyu Chen, Yu Jun Tan   +6 more
wiley   +1 more source

The Multifaceted Importance of Amphibians: Ecological, Biomedical, and Socio-Economic Perspectives. [PDF]

Biology (Basel)
Wickramasingha B, West J, Bellanthudawa BKA, Graziano MP, Surasinghe TD.   +4 more
europepmc   +1 more source

Protocol‐Agnostic Meta Key Distribution for Encrypted Wireless Communications Enabled by Space‐Time‐Coding Metasurface

Advanced Science, EarlyView.
This paper presents a programmable metasurface‐based Meta Key Distribution (MKD) system for secure, protocol‐independent key exchange in indoor wireless settings. By embedding entropy into the wireless channel, it enables lightweight, compatible cryptographic key generation.
Xinyu Li, Long Chen, Guanxiong Shen, Kezhan Zhao, Ze Gu, Qian Ma, Jian Wei You, Tie Jun Cui   +7 more
wiley   +1 more source

Nonlinear thinking in ecology and evolution: applying the threshold elemental ratio across levels of ecological organization. [PDF]

Oecologia
Tumolo BB, Olson CR, Larson EI, Halvorson HM, Wagner CE, Krist AC, Osburn FS, Moody EK, Rock LA, Ogbenna UVC, Wess EN, Najev B, Pignatelli AJ, Corman JR.   +13 more
europepmc   +1 more source