Results 61 to 70 of about 1,803,005 (297)
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Rivista Italiana di Informatica e Diritto, 2022 This essay tries to analyze the complex challenge of introducing governance measures to preserve the utility of the Internet, the safety of citizens and to hold accountable those who abuse the privilege of access to the Internet.
Vinton G. Cerf
doaj +1 more source
Social preferences for ecosystem services in a biodiversity hotspot in South America [PDF]
, 2019 Identifying which ecosystem services are relevant to different stakeholders and understanding stakeholders’ perceptions of such services is useful for making informed decisions, especially in regions of the world where the achievement of biodiversity ...
Bidegain, Iñigo +4 more
core +2 more sources
Molecular Oncology, EarlyView.Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li +12 more
wiley +1 more source
Anthropogenic impact on the Taldykol lake system in the city of Nur-Sultan
RUDN Journal of Ecology and Life Safety, 2022 The article describes study of the hydrochemistry of Taldykol lake system, consisting of the Big and Small Taldykol lakes, in the city of Nur-Sultan. The aim of the work is to assess the anthropogenic impact on the ecosystem of steppe wetlands located in
Lyailya Kh. Akbayeva +2 more
doaj +1 more source
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Upscaling key ecosystem functions across the conterminous United States by a water-centric ecosystem model [PDF]
, 2011 We developed a water-centric monthly scale simulation model (WaSSI-C) by integrating empirical water and carbon flux measurements from the FLUXNET network and an existing water supply and demand accounting model (WaSSI).
Caldwell, Peter +11 more
core +4 more sources
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Understanding of Digital Transformation and Its Background
Maketingu Janaru, 2020 Recent evolutions in technology have enabled the rapid growth of digital companies through ecosystems, which have generated both threats and opportunities for existing companies who are struggling to adapt themselves to this rapidly changing environment.
Norio Imai
doaj +1 more source
Ecosystem Competition and the Antitrust Laws [PDF]
, 2019 I. Introduction II. Three Examples of Ecosystem Competition ... A. Middleware and Operating Systems ... B. E-Books and Tablets … C. Connected and Automated Vehicles III. How Ecosystem Competition Enhances Consumer Welfare IV.
Crane, Daniel A.
core +1 more source