Results 31 to 40 of about 178,539 (219)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Ecosystems as an innovative business model in conditions of digital transformation

open access: yesВестник Северо-Кавказского федерального университета
Introduction. A sustainable strategic trend today is the creation of ecosystems – innovative business models. Ecosystem companies are becoming new objects of economic research.
O. V. Godina   +2 more
doaj   +1 more source

Change of paradigms in management of fishery: from conception to realization?

open access: yesИзвестия ТИНРО, 2017
A new system of views on effective management in fisheries has been developed by fishery science in the beginning of the 21st century under the aegis of FAO (UN). It claims the principle of ecosystem approach in fishery studies. However, this approach is
Oleg A. Ivanov
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

DOMAIN ASSESSMENT OF BALI SARDINELLA RESOURCES THROUGH ECOSYSTEM APPROACH AT ARCHIPELAGO FISHING PORT (PPN) PENGAMBENGAN

open access: yesJurnal Teknologi Perikanan dan Kelautan
Bali sardinella is a fish species that contributes greatly to the Archipelago Fishing Port (PPN) Pengambengan. The potential of Bali sardinella fishery resources is abundant and of high economic value.
Rakhma Fitria Larasati   +10 more
doaj   +1 more source

Fishing strategies and the Ecosystem Approach to Fisheries in the eastern Mediterranean Sea

open access: yesScientia Marina, 2014
The sustainable use of aquatic living resources is the cornerstone of the ecosystem approach to fisheries management (EAF). Excess fishing effort leading to the degradation of fishery resources and significant economic waste is globally recognized by ...
Christos D. Maravelias   +2 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

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