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The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Ecosystem extent mapping in a global monitoring context
The vital role of ecosystems in maintaining biosphere stability is now recognised globally. Updates in policy frameworks on biodiversity and environmental decline include information on ecosystem extent (EE) as a core assessment indicator, e.g., the Global Biodiversity Framework indicator A2 ‘Extent of natural ecosystems’.
Polina Tregubova +14 more
openaire +3 more sources
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Toward development of ecosystem asset accounts at the national level
Ecosystem accounting has become one of the key components in the revision of international statistical standards. Expansion of the System of Environmental-Economic Accounting for ecosystem services follows the rapid progress of science in this area as ...
Dava Vačkářů +1 more
doaj +1 more source
Mapping Ecosystem Services of Forest Stands: Case Study of Maamora, Morocco
The concept of ecosystem services (ES) is increasingly used to analyze the relationships and interactions between humans and nature. Understanding the ecosystem services’ flow and the ecosystems’ capacity to generate these services is an essential ...
Abdelkader Benabou +6 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
The article enhances the knowledge base for the assessment of urban ecosystem services, within the United Nations System of Environmental-Economic Accounting Ecosystem Accounting (SEEA EA), recently adopted as an international statistical standard. The SEEA EA is based on spatial extent accounts (area of ecosystems) and biophysical condition accounts ...
Garnåsjordet, Per Arild +5 more
openaire +3 more sources
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source

