Results 181 to 190 of about 536,813 (304)

Microbial conservation is essential for sustaining ecosystem functions and services. [PDF]

Proc Natl Acad Sci U S A
Junker RR, Farwig N.
europepmc   +1 more source

Ecological restoration of habitats invaded by Leucanthemum vulgare that alters key ecosystem functions. [PDF]

PLoS One, 2021
Khan MA, Hussain K, Shah MA.
europepmc   +1 more source

Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions

Advanced Science, EarlyView.
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang, Wenzhi Wang, Dongjiao Wang, Qibin Wu, Youxiong Que   +4 more
wiley   +1 more source

Effects of Biodiversity Loss on Freshwater Ecosystem Functions Increase With the Number of Stressors. [PDF]

Glob Chang Biol
Schäfer RB, Baikova D, Bayat HS, Beermann AJ, Berger SA, Boenigk J, Brauns M, Burfeid-Castellanos A, Cardinale BJ, David GM, Feckler A, Feld CK, Fink P, Gessner MO, Hadziomerovic U, Hering D, Le TTY, Macaulay SJ, Madariaga GM, Serge Mayombo NA, Pimentel IM, Orr JA, Osakpolor S, Schlenker A, Sures B, Vermiert AM, Vos M, Weitere M, Schürings C.   +28 more
europepmc   +1 more source

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

Advanced Science, EarlyView.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun, Haili Hu, Long Chen, Yuan Gao, Peng Sun, Liming Chen   +5 more
wiley   +1 more source

Energy flows reveal declining ecosystem functions by animals across Africa. [PDF]

Nature
Loft T, Oliveras Menor I, Stevens N, Beyer R, Clements HS, Santini L, Thomas S, Tobias JA, Malhi Y.   +8 more
europepmc   +1 more source

Cancer‐Associated Fibroblasts Promote Tumor Immunosuppression in Hepatocellular Carcinoma via the NNMT‐ANGPTL4 Axis

Advanced Science, EarlyView.
ABSTRACT Background & Aims: Cancer‐associated fibroblasts (CAFs) drive immunosuppression in hepatocellular carcinoma (HCC). However, their metabolic regulation remains poorly defined. We investigated the role of nicotinamide N‐methyltransferase (NNMT) in CAFs. Approach & Results: High NNMT expression in CAF tissues was confirmed by western blotting and
Shounan Lu, Shanjia Ke, Hongjun Yu, Zhanzhi Meng, Miaoyu Bai, Yanan Xu, Hui Zhu, Jinwen Yang, Baolin Qian, Bing Yin, Chaoqun Wang, Zhigang Feng, Zhongyu Li, Yongzhi Zhou, Zihao Li, Xinglong Li, Yongliang Hua, Yao Fu, Wei Tang, Yaohua Wu, Yong Ma   +20 more
wiley   +1 more source

Rooting for function: community-level fine-root traits relate to many ecosystem functions. [PDF]

New Phytol
Barry KE, Hennecke J, Weigelt A, Bergmann J, Bruelheide H, Freschet GT, Iversen CM, Kuyper TW, Laughlin DC, McCormack ML, Roumet C, van der Plas F, van Ruijven J, Wijsmuller R, Auge H, Eisenhauer N, Haase J, Nock CA, Oelmann Y, Wilcke W, Mommer L.   +20 more
europepmc   +1 more source

Disentangling Responses of the Subsurface Microbiome to Wetland Status and Implications for Indicating Ecosystem Functions. [PDF]

Microorganisms, 2021
Gao J, Liu M, Shi S, Liu Y, Duan Y, Lv X, Bohu T, Li Y, Hu Y, Wang N, Wang Q, Zhuang G, Zhuang X.   +12 more
europepmc   +1 more source

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

Advanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang, Wanyi Xiao, Hongru Shen, Fenge Li, Ting Li, Weihong Zhang, Haotian Liu, Ziwei Gao, Hongyu Wang, Xiubao Ren, Kexin Chen, Xiangchun Li, Jilong Yang   +12 more
wiley   +1 more source