Results 221 to 230 of about 7,383,481 (254)

Spatiotemporal CD8⁺ T-Cell Dynamics: Clonal Replacement and Expansion as Determinants of Sustainable Antitumor Response. [PDF]

Cancer Sci
Ueha S, Aoki H, Takahashi M, Shichino S, Matsushima K.   +4 more
europepmc   +1 more source

Translational Barriers and AI‐Driven Challenges of Microfluidics‐Enabled Wearables and Implantable Systems in Personalized Medicine

Advanced Science, EarlyView.
An integrative review of microfluidics‐enabled wearables and implantable systems reveals a single‐track translation pipeline, bridging functional biomaterials with clinical utility. Dynamic feedback loops driven by artificial intelligence advance diagnostics toward personalized closed‐loop theranostics.
Ke Huang, Ching Yin Fong, Xin Huang, Bee Luan Khoo   +3 more
wiley   +1 more source

Primary care-based post diagnostic dementia care in England: modelling and scaling up evidence-based models for efficient future care. [PDF]

Age Ageing
Walbaum M, King D, Robinson L, Knapp M, Wittenberg R.   +4 more
europepmc   +1 more source

Low SLC8A1 in Colorectal Cancer Dictates Radiotherapy Resistance Through Calcium‐Dependent ANXA2+sEVs Driving M2 Polarization of TAMs

Advanced Science, EarlyView.
SLC8A1 deficiency in colorectal cancer cells increases intracellular calcium signaling, promoting the secretion of ANXA2‐enriched small extracellular vesicles. These vesicles reprogram tumor‐associated macrophages towards an M2 phenotype, which in turn fosters a tumor microenvironment conducive to radioresistance and is associated with poor patient ...
Yimin Fang, Jinghan Zhu, Qian Xiao, Qichun Wei, Xiujing He, Ping Li, Kai Jiang, Yue Liu, Yeting Hu, Weiwei Yu, Chuansheng Guo, Sheng Chen, Jian Zhao, Siqi Dai, Jingsun Wei, Hang Yang, Tongtong Bu, Kefeng Ding, Haiyan Chen   +18 more
wiley   +1 more source

A spectrum of gut microbiota signatures predicts long-term health status. [PDF]

Bioinformatics
Lindgren H, Ross C, Ruuskanen M, Salomaa V, Knight R, Niiranen T, Havulinna A, Lahti L.   +7 more
europepmc   +1 more source

Autophagy Orchestrates Anti‐Tumor Immunity to Enhance Chemosensitivity via the FBXW2/C/EBPβ/TIMP‐2 Axis in Colorectal Cancer

Advanced Science, EarlyView.
Chemotherapy leverages tumor‐cell autophagy to reshape the colorectal cancer immune microenvironment. Autophagy degrades FBXW2 to promote C/EBPβ‐mediated TIMP‐2 transcription and MMP‐9 suppression, driving intra‐tumoral CD8+ T‐cell infiltration. Targeting MMP‐2/9 or restoring TIMP‐2 overcomes chemo‐resistance in autophagy‐deficient tumors. ABSTRACT The
Bing Cheng, Chaoying Wei, Zhitong Niu, Jinxin Chen, Guojie Long, Yingzhen Weng, Qiufeng Liu, Yue Jiang, Panpan Wang, Ronghua Zhang, Qiang Yu, Xiaojian Wu, Wenyu Wang   +12 more
wiley   +1 more source

Themed issue on artificial intelligence in managed care pharmacy. [PDF]

J Manag Care Spec Pharm
Miller AM, Ortman E, Onukwugha E, Clark C, Happe LE.   +4 more
europepmc   +1 more source

Multitrophic interaction networks mediate biodiversity effects on ecosystem multifunctionality. [PDF]

Nat Commun
Albert G, Staab M, Luo A, Anttonen P, Beugnon R, Cesarz S, Chen J, Eisenhauer N, Erfmeier A, Fornoff F, Guo P, Härdtle W, Hönig L, Jiang L, Klein AM, Li Y, Li Y, Li Q, Liu L, Ma K, von Oheimb G, Rutten G, Scholten T, Seitz S, Singavarapu B, Trogisch S, Wang MQ, Wang P, Wu D, Wubet T, Yang X, Yu M, Zhang N, Schmid B, Bruelheide H, Liu X, Zhu CD, Schuldt A.   +37 more
europepmc   +1 more source

Ecosystem Resilience and Land-Use Governance: Remote Sensing Insights for Environmental Management in a Tropical Dry Forest. [PDF]

Environ Manage
Nascimento da Silva L, Israel de Souza B.   +1 more
europepmc   +1 more source

Next-generation soil monitoring: linking metagenomics, biosensors, and ecological modeling for sustainable agriculture. [PDF]

Front Microbiol
Romero-Arguelles R, Ruiz-Ayma G, Rodriguez-Castro VA, Gonzalez-Rojas JI, Gomez-Govea MA.   +4 more
europepmc   +1 more source