Results 31 to 40 of about 25,803 (221)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Spatial variation in non-structural carbohydrates reserves of pine species along climatic gradients: A global synthesis

Forest Ecosystems
Non-structural carbohydrates (NSCs) are crucial for tree growth and survival under climatic stress, yet their spatial dynamics across broad climate gradients remain unclear.
Yanfang Wang, Fang Wang, Mai-He Li, Yating Li, Yu Xia, Yan-Li Zhang, Yunpeng Luo, Xiaohua Gou   +7 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Opportunities for improved detection of linked hydroclimate‐ecosystem dynamics in Arctic catchments

Frontiers in Environmental Science
Climate warming is transforming Arctic landscapes through changes in the cryosphere and water systems that together contribute to alterations in the structure and function of ecosystems.
Johanna Mård, Torben Røjle Christensen, Torben Røjle Christensen, Joseph M. Culp, Willem Goedkoop, Hannu Marttila, Niels Martin Schmidt, Timo Vihma   +7 more
doaj   +1 more source

Progress in observational studies on carbon dioxide fluxes between the atmosphere and the surface on the Qinghai-Xizang Plateau [PDF]

Gaoyuan qixiang
As a globally significant ecological security barrier and climate-sensitive region， the Qinghai-Xizang Plateau （QXP） plays a crucial role in regional and global carbon cycles.
Yaoming Ma, Weimo Li, Binbin Wang, Zeyong Hu, Weiqiang Ma, Yuyang Wang, Zhipeng Xie, Bin Ma, Nan Yao, Wenqing Zhao, Xingdong Shi, Lijun Sun, Yue Xu, Changrong Tan, Qiang Zhang, Xiaowen Zhou, Zhengling Cai, Xuan Li
doaj   +1 more source

Field Report from Collaborative Research Center 1625: Heterogeneous Research Data Management Using Ontology Representations

Advanced Engineering Materials, EarlyView.
A unified research data management framework for heterogeneous materials data is presented. The system integrates multimodal datasets using ontologies and knowledge graphs, enabling interoperability and FAIR (findable, accessible, interoperable, reusable) data principles. By linking data across scales and workflows, it supports reproducible, Artifitial
Doaa Mohamed, Samuel García Vázquez, Behnam Mardani, Victor Dudarev, Alfred Ludwig, Maribel Acosta, Markus Stricker   +6 more
wiley   +1 more source

Developing an environmental research platform in the Karoo at the Square Kilometre Array

South African Journal of Science, 2021
A part of the Square Kilometre Array (SKA) will be constructed in the northern Karoo of South Africa on approximately 135 000 ha of land. This land is formerly privately owned rangelands (farms) that were purchased by the South African National Research ...
Helga van der Merwe, Suzanne J. Milton, W. Richard J. Dean, Tim G. O'Connor, Joh R. Henschel   +4 more
doaj   +1 more source

The PRIMA Thesaurus for Materials Science and Engineering

Advanced Engineering Materials, EarlyView.
The PRIMA Thesaurus is a structured vocabulary designed to improve how materials science data is described and shared. Developed with input from multiple experts, it enables clear documentation of research workflows, data exchange, and reuse across platforms.
Rossella Aversa, Alexey Boubnov, Dario De Angelis, Catriona Eschke, Maximilian Kabbe, Felix Kraus, Mirco Panighel, Richard Thelen, Davide Valentinis   +8 more
wiley   +1 more source

Current Status and Challenges in Data Collection for Aerospace Coatings Deposited by Plasma Spraying

Advanced Engineering Materials, EarlyView.
An innovative approach has been integrated into the GRENAT project to optimize plasma spraying and coating performance. Raw materials are accelerated and melted in the plasma generated by torches, creating coatings. Monitoring sensors collect process data which are combined with ex situ characterization data.
Lila Randriamananjara, Vincent Rat, Quentin Dubreuil, Patrice Valorge, Simon Goutier, Alain Denoirjean, Olivier Messe, Céline Ruelle, Jean‐Philippe Poli   +8 more
wiley   +1 more source