Results 51 to 60 of about 856,653 (305)

Ecosystem Pipelines: Collective Action in Entrepreneurial Ecosystems [PDF]

Entrepreneurial ecosystems comprise a range of different actors, structures, and processes that support entrepreneurs in starting and growing their ventures.
Hruskova, Michaela
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Socio-Ecological Networks: A Lens That Focuses Beyond Physics

Frontiers in Ecology and Evolution, 2021
Contemporary systems ecology has long been occupied with mechanical explanations of behavior; however, the physical theory that undergirds such explanations has certain limits.
Robert E. Ulanowicz, Robert E. Ulanowicz
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Knowledge, Attitude and Practice in Water Resources Management among Smallholder Irrigators in the Tsavo Sub-Catchment, Kenya

Resources, 2019
The rising demand for food production in a changing climate impacts water resources negatively in semi-arid agro-ecosystems. In the Tsavo sub-catchment of Kenya, this is compounded by a surging population and expansion of cropping as a land use; leading ...
Francis Oremo, Richard Mulwa, Nicholas Oguge   +2 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Confronting Feedbacks of Degraded Marine Ecosystems

, 2012
In many coastal areas, marine ecosystems have shifted into contrasting states having reduced ecosystem services (hereafter called degraded). Such degraded ecosystems may be slow to revert to their original state due to new ecological feedbacks that ...
Thyresson, Matilda,, Folke, Carl, de la Torre-Castro, Maricela,, Blenckner, Thorsten,, Folke, C., Steneck, Robert S., Eklöf, Johan S.,, de la Torre-Castro, M., Troell, M., Troell, Max, Nystrom, M., Österblom, Henrik,, Blenckner, T., Eklöf, Johan,, Norström, Albert V., Norstrom, A. V., Thyresson, M., Nyström, Magnus,, Osterblom, H., Steneck, R. S.   +19 more
core   +1 more source

Plumbing the global carbon cycle: Integrating inland waters into the terrestrial carbon budget [PDF]

, 2007
Because freshwater covers such a small fraction of the Earth’s surface area, inland freshwater ecosystems (particularly lakes, rivers, and reservoirs) have rarely been considered as potentially important quantitative components of the carbon cycle at ...
Striegl, R.G., C. M. Duarte, J. A. Downing, Tranvil, L., Duarte, C.M., Prairie, Y.T., Kortelainen, P., Middelburg, J. J., W. H. McDowell, J. J. Middelburg, Tranvik, Lars,, Y. T. Prairie, Caraco, N. F., Melack, J., L. J. Tranvik, J. J. Cole, Middelburg, J.J., Caraco, N., Downing, J.A., R. G. Striegl, Prairie, Y. T., McDowell, W. H., Duarte, C. M., N. F. Caraco, Cole, J., P. Kortelainen, Cole, J.J., Striegl, R. G., Downing, J. A., J. Melack, McDowell, W.H.   +30 more
core   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi, Giorgio Ricciardiello Mejia, Andre Metzger, Kang Hyun Ryu, Salonee Marwaha, Eva Grzegorczyk, Li Zhou, Eliana Jacobs, Boris Gilyadov, Claudia Kunney, Liqhwa Ncube, Ankit Parekh, Emmanuel Mignot, Fanny M. Elahi, Joseph Winer, Kathleen Poston, Andreas Brink‐Kjaer, Emmanuel H. During   +17 more
wiley   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source