Results 121 to 130 of about 168,874 (283)
A Human-Derived Monoclonal Antibody Targeting Extracellular Connexin Domain Selectively Modulates Hemichannel Function [PDF]
, 2019 Connexin hemichannels, which are plasma membrane hexameric channels (connexons) composed of connexin protein protomers, have been implicated in a host of physiological processes and pathological conditions. A number of single point pathological mutations
Buratto, Damiano +12 more
core +1 more source
Molecular basis of hypohidrotic ectodermal dysplasia: an update
Journal of Applied Genetics, 2015 Recent advances in understanding the molecular events underlying hypohidrotic ectodermal dysplasia (HED) caused by mutations of the genes encoding proteins of the tumor necrosis factor α (TNFα)-related signaling pathway have been presented.
W. Trzeciak, R. Koczorowski
semanticscholar +1 more source
, 2016 ABSTRACT Background and Setting: Hypohidrotic (anhidrotic) ectodermal dysplasia (HED) is a congenital syndrome that exhibits features of oligodontia/anodontia, scant hair and reduced sweating. It has an estimated prevalence of 1/17000, worldwide. Presented here is a case of HED in a 22-year-old male patient who had congenitally missing teeth.
DR. Saurabh Shekhar, MDS [1] +2 more
openaire +2 more sources
The Ectodermal Dysplasias : Severe Palmoplantar Hyperkeratosis And Chronic Angular Cheilitis
Indian Journal of Dermatology, 2003 The ectodermal dysplasias are congenital, non-progressive and diffuse disorders affecting primarily the tissues derived from ectoderm. Over a period, their classification has become confusing due to indiscriminate use of them â€ectodermal ...
Mahajan Vikram K +2 more
doaj
Case Reports in Dentistry, 2012 Hereditary ectodermal dysplasia is a rare group of inherited disorders characterized by aplasia or dysplasia of two or more tissues of ectodermal origin such as hair, nails, teeth, and skin.
Neha Jain +5 more
doaj +1 more source
Tumor Necrosis Factors and Chemokines in Hair Development [PDF]
, 2012 Several embryonic organs, such as the hair follicle, develop as appendages of the ectoderm, the outermost layer of the embryo. These organs develop as a result of reciprocal tissue interactions between the surface epithelium and the underlying mesenchyme.
Lefebvre, Sylvie
core
p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation [PDF]
, 2006 Heterozygous germline mutations in p63, a transcription factor of the p53 family, result in abnormal morphogenesis of the skin and its associated structures, including hair follicles and teeth.
James, M. +5 more
core +1 more source
Journal of Indian Academy of Oral Medicine and Radiology, 2012 Ectodermal dysplasia is a hereditary disorder characterized by developmental dystrophies of ectodermal derivatives- It is characterized by triad of signs comprising sparse hair, abnormal or missing teeth and inability to sweat.
M Naveen Kumar +5 more
doaj +1 more source
Mini-implants: alternative for oral rehabilitation of a child with ectodermal dysplasia.
Brazilian Dental Journal, 2015 Ectodermal dysplasia is a rare congenital disease that affects several structures of ectodermal origin. The most commonly related oral characteristics are hypodontia, malformed teeth and underdeveloped alveolar ridges.
B. Mello +5 more
semanticscholar +1 more source
Hereditary Ectodermal Dysplasia in Two Identical Siblings
Acta Medica BulgaricaPrimary defects in two or more ectodermally-derived tissues during embryonic development characterize ectodermal dysplasia, a vast, varied group of inherited illnesses. Skin, hair, nails, eccrine glands, and teeth are the primary tissues affected.
Sarkar A. S., Rao K., Ajila V.
doaj +1 more source