Results 201 to 210 of about 99,533 (328)

Retatrutide for the treatment of obesity, obstructive sleep apnea and knee osteoarthritis: Rationale and design of the TRIUMPH registrational clinical trials

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 83-93, January 2026.
Abstract Aims Retatrutide, a novel synthetic molecule, is a triple agonist activating the glucose‐dependent insulinotropic polypeptide, glucagon‐like peptide‐1 and glucagon receptors. The TRIUMPH clinical development program evaluates its safety and efficacy concurrently for the treatment of obesity and two related complications—obstructive sleep apnea
Kathryn Giblin   +8 more
wiley   +1 more source

Carcinoma of unknown primary site and ectopic pregnancy diagnosed at laparoscopic surgery: a rare coexistence [PDF]

open access: bronze, 2018
Munetoshi Akazawa   +4 more
openalex   +1 more source

The role of UPR‐related long noncoding RNAs in development of endocrine resistance in breast cancer

open access: yesInternational Journal of Cancer, Volume 157, Issue 12, Page 2434-2446, 15 December 2025.
Abstract Breast cancer patients who express estrogen receptor α (ER) typically receive endocrine therapy as a first‐line treatment. Most ER‐positive breast cancer patients initially respond to endocrine therapy, but up to 40% of patients develop resistance over time, and the main mechanism is aberrant activation of ER signaling pathways.
Wen Liu, Sahil Gupta, Sanjeev Gupta
wiley   +1 more source

Tubal Ectopic Pregnancy: From Diagnosis to Treatment. [PDF]

open access: yesBiomedicines
Papageorgiou D   +3 more
europepmc   +1 more source

Nociceptive Nerve‐Derived CGRP Exacerbates Uterine Fibrogenesis in Adenomyosis by Promoting CD140b+ CD146+ Fibroblast Differentiation

open access: yesAdvanced Science, Volume 12, Issue 45, December 4, 2025.
This study investigates adenomyosis fibrosis in relation to nociceptive nerves. Nociceptive nerve‐secreted CGRP promotes RAMP1hi CD140b+ CD146+ fibroblast differentiation into myofibroblasts through ERK activation, causing severe fibrosis. Rimegepant‐induced CGRP/RAMP1 signaling blockade alleviates fibrosis and restores fertility in a mouse model. This
Zi Ye   +11 more
wiley   +1 more source

Cervical Ectopic Pregnancies after Spontaneous Conception: Case Reports

open access: hybrid, 2018
Simona Anzhel   +5 more
openalex   +2 more sources

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