Results 271 to 280 of about 99,533 (328)

Janus Kinase Inhibitors During Pregnancy and Adverse Drug Reactions: A Pharmacovigilance Disproportionality Analysis in VigiBase

open access: yesClinical and Translational Science, Volume 18, Issue 12, December 2025.
ABSTRACT Janus kinase inhibitors (JAKIs) are immunomodulatory drugs used for autoimmune and inflammatory conditions. Their potential impact on pregnancy and fetal development remains a concern due to placental transfer and potential disruption of cytokine and growth factor signaling, with limited human data.
Nazanin Abolhassani   +7 more
wiley   +1 more source

In vivo modeling of lethal congenital contracture syndrome 1 suggests pathomechanisms in cellular stress responses

open access: yesThe FEBS Journal, Volume 292, Issue 23, Page 6365-6399, December 2025.
GLE1 plays a direct role mRNA regulation, translation, and formation of cytosolic stress granules. GLE1 dysfunction has been associated with devastating diseases, including lethal congenital contracture syndrome 1(LCCS1), a rare disorder enriched in isolated populations.
Tomáš Zárybnický   +22 more
wiley   +1 more source

The Promise of Exosomes in Cardiac Repair: When ‘Best Things Come in Small Packages’

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 23, December 2025.
ABSTRACT Myocardial ischaemia continues to be a predominant global cause of mortality, leaving survivors with compromised quality of life and significant loss of functional cardiomyocytes. The main therapeutic approach, which attempts to restore heart function, generally involves myocardial reperfusion.
Anthony Yazbeck   +6 more
wiley   +1 more source

Living with acuteness in chronic illness: The temporal underpinnings of endometriosis

open access: yesMedical Anthropology Quarterly, Volume 39, Issue 4, December 2025.
Abstract This article explores how acuteness is experienced by people with endometriosis in Finland. Drawing on in‐depth interviews as well as anonymous written endometriosis stories, we trace instances when the sense of chronicity and cyclicality of endometriosis is disrupted by a possibility of risk to life. These instances include when endometriosis
Venla Oikkonen, Elina Helosvuori
wiley   +1 more source

A Case Report of Chronic Ectopic Pregnancy: A Silent Entity With a Surgical Diagnosis. [PDF]

open access: yesCureus
Sadek Azar R   +4 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy