Results 91 to 100 of about 8,885 (237)

Normalization of Hemoglobin, Lactate Dehydrogenase, and Fatigue in Patients with Paroxysmal Nocturnal Hemoglobinuria Treated with Pegcetacoplan

open access: yesDrugs in R&D
Background and Objectives We determined normalization rates for hemoglobin, lactate dehydrogenase (LDH), and fatigue in patients with paroxysmal nocturnal hemoglobinuria (PNH) treated with pegcetacoplan (PEG) in the PEGASUS (NCT03500549) and PRINCE ...
Brian P. Mulherin   +3 more
doaj   +1 more source

Conditional deletion of the multiple sclerosis susceptibility gene ATXN1 identifies cell‐autonomous effects in the B‐cell compartment

open access: yesThe FEBS Journal, Volume 293, Issue 5, Page 1459-1477, March 2026.
Ataxin‐1 is a polyglutamine protein associated with the etiology of spinocerebellar ataxia type 1 (SCA1) that has been recently found implicated in the risk of developing the autoimmune disorder multiple sclerosis (MS). Here, we took a conditional knockout approach to ablate ataxin‐1 exclusively in the B‐cell compartment and we found that this protein ...
Jonathan Jacob Carver   +3 more
wiley   +1 more source

Preserving Residual Kidney Function in Haemodialysis: Current Practices, Challenges, and Perspectives From Renal Clinicians

open access: yesJournal of Renal Care, Volume 52, Issue 1, March 2026.
ABSTRACT Background Residual kidney function in patients receiving haemodialysis is associated with improved survival, reduced cardiovascular risk and better quality of life. Yet, clinical guidelines on its preservation are limited, and local practices remain unclear.
Lijun Zhong   +6 more
wiley   +1 more source

Exercise during pregnancy modulates infant cellular and whole‐body adiposity

open access: yesPhysiological Reports
Non‐pharmaceutical interventions are needed to target the growing intergenerational cycle of obesity. We aimed to determine whether in utero exposure to different exercise doses during pregnancy directly reduces infant cellular and whole‐body adiposity ...
Alex Claiborne   +11 more
doaj   +1 more source

A Secure Communication Framework for ECUs

open access: diamond, 2017
Ali Shuja Siddiqui   +3 more
openalex   +2 more sources

Design and development of an intelligent zone based master electronic control unit for power optimization in electric vehicles

open access: yesScientific Reports
The development of electric vehicles (EVs) has been incremental because EVs satisfy a significant demand for energy sources. Electronic control unit (ECU) is an important component that processes the electric signals received from various sensors for ...
A. Prabhakaran   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy