Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore +20 more
wiley +1 more source
Spiritual Care at the Crossroads: An Ecumenical White Paper on the Future of Christian Healthcare Chaplaincy. [PDF]
Peng-Keller S +13 more
europepmc +1 more source
A History of Development of Medical Missions and Catholic Evangelization in Sub-Saharan Africa From the Early Twentieth Century to the Present: Tracing Some Representative Founders and Orders in the Context of the Twentieth Century Church. [PDF]
Dailor EM.
europepmc +1 more source
Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang +16 more
wiley +1 more source
Interreligious and Ecumenical Dialogue at Vatican II: Some Rethinking Required [PDF]
Phan, Peter
core +1 more source
Ecumenical Movements in Croatia after the SecondVatican Council
Značajan pomak i otvaranje ekumenskoj ideji i pokretu koji je za Katoličku crkvu učinio Drugi vatikanski koncil naišli su na veliki odjek u Hrvatskoj. Osobito je to vidljivo u prvim godinama nakon Koncila kada je u Crkvi u Hrvata pokrenut niz događanja koja su trebala započeti s ekumenizmom na prostoru bivše Jugoslavije.
openaire +1 more source
Dealing with Highly Pathogenic Avian Influenza: An Impending Crisis. [PDF]
Lin R, Lu L, Lycett S, Liu W, Li J.
europepmc +1 more source
Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann +15 more
wiley +1 more source
Ecumenical and Confessional Writings Volume 1: The Coming Christ and Church Traditions/ After the Council [PDF]
Schlink, Edmund
core +1 more source
CORR® Curriculum-Orthopaedic Education: How Should Residents Be Using Research Protected Time for Scholarly Activities? [PDF]
Dougherty PJ.
europepmc +1 more source

