Results 31 to 40 of about 44,003 (342)

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Journey from isolation

open access: yesHTS Teologiese Studies/Theological Studies, 2011
Since the Ottawa Consultation in 1982, the relationship between the Nederduitsch Hervormde Kerk van Afrika (NHKA) and the World Alliance of Reformed Churches (WARC) was nonexistent. In the NHKA it became progressively clear that it would be impossible to
Wim A. Dreyer
doaj   +1 more source

Enlightenment and Ecumenism [PDF]

open access: yes, 2009
The contribution of monasticism to Christian theology\u27s framework in almost all periods is undisputed. However, the eighteenth century as a period of monastic theology is still—unjustly—overlooked.
Lehner, Ulrich
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

COOPERAÇÃO E TRANSFORMAÇÃO: REFLEXÕES SOBRE O PANORAMA DA COOPERAÇÃO ECUMÊNICA COMO FERRAMENTA DE AFIRMAÇÃO E PROMOÇÃO DE DIREITOS

open access: yesÚltimo Andar, 2016
O presente trabalho visa destacar a importância da cooperação ecumênica na afirmação e promoção de direitos. A delimitação utilizada é entre 1994 e 2013, na América Latina.
Darli Alves de Souza
doaj  

Pilgrims and Wayfarers to, at and from Ecumenical Gatherings and Encounters [PDF]

open access: yes, 2014
This article studies a topic which has not been treated previously. The physical experience of the journey—to the ecumenical encounter, the stay in a particular venue for prayer, dialogue or for joint initiatives, and the journey back home—becomes the ...
Scerri, Hector
core  

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

Evolution of the Official Position of the Roman Catholic Church towards the Ecumenical Movement According the Results of the Second Vatican Council

open access: yesAstra Salvensis, 2019
It is common and well-known fact that Holy See always identified itself as one the holy, catholic and apostolic Church. Roman Pontiffs were against ecumenical ideas and strongly condemned the movement which was organized in the beginning of XX-th century
Denis MELKOV
doaj  

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