Results 31 to 40 of about 44,151 (314)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Ecumenism as Hope: The Prophetic Role and the Eschatological Function of the Church
Religions, 2023 The article is structured around one of the questions that has been at the forefront of controversies in the orthodox church in recent years: why is ecumenical dialogue necessary and why “must” we engage in it? The answer can be simple: because it is the
Cristian-Sebastian Sonea
doaj +1 more source
Living in to its Name and Living up to its Legacy: The public practical theology of KAIROS [PDF]
, 2015 KAIROS Canada looks hopefully towards the emerging challenges of continuing public practical theology in a pluralistic, post-apology time and ...
Henry, Jennifer
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Tacit dewesternisation in the ecumenical movement: The example of the World Council of Churches
HTS Teologiese Studies/Theological StudiesDewesternisation is a concept still undergoing conceptual clarification and refinement. It is used in different theoretical approaches, often differently meant and assessed.
Piotr Kopiec
doaj +1 more source
HTS Teologiese Studies/Theological Studies, 2011 Since the Ottawa Consultation in 1982, the relationship between the Nederduitsch Hervormde Kerk van Afrika (NHKA) and the World Alliance of Reformed Churches (WARC) was nonexistent. In the NHKA it became progressively clear that it would be impossible to
Wim A. Dreyer
doaj +1 more source
The Shifting Ecumenical Landscape at the 2017 Reformation Centenary [PDF]
, 2017 The 2017 Reformation Centenary is the first commemoration to take place during the ecumenical age and marks fifty years of Lutheran–Roman Catholic dialogue.
Wood, Susan K.
core +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source