Results 141 to 150 of about 129,126 (313)

The International Guideline for the Definition, Classification, Diagnosis and Management of Urticaria

open access: yesAllergy, EarlyView.
ABSTRACT This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...
T. Zuberbier   +221 more
wiley   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter   +20 more
wiley   +1 more source

Eczema in early childhood increases the risk of allergic multimorbidity

open access: yesClinical and Translational Allergy
Background Eczema in early childhood is associated with the development of subsequent allergic diseases, including food allergy (FA), asthma and hay fever.
L. A. Miltner   +3 more
doaj   +1 more source

Health service use among children with and without eczema, asthma, and hay fever

open access: yes, 2016
Lene Hammer-Helmich,1,2 Allan Linneberg,1,3,4 Simon Francis Thomsen,5,6 Line Tang,1 Charlotte Glümer1,7 1Research Center for Prevention and Health, The Capital Region of Denmark, Copenhagen, 2Department of Real World Evidence and Epidemiology, H ...
Hammer-Helmich L   +4 more
core  

What is “eczema”?

open access: yesThe Journal of Dermatology
AbstractEczema is the most common category of inflammatory skin disorders as dermatologists see many patients with eczematous diseases in daily practice. It is characterized by the three major morphological features: multiple‐pinpoint condition, polymorphism, and itch.
Yoshiki Tokura   +3 more
openaire   +2 more sources

Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema

open access: yesAllergy, EarlyView.
This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery   +25 more
wiley   +1 more source

Autosomal Dominant Hyper‐IgE Syndrome Patients Retain IL10‐Producing preTh17‐Cells That Are Activated by Opportunistic Pathogens and Support IgE Production

open access: yesAllergy, EarlyView.
IL‐10 producing CCR6+Th‐cells are central memory T‐cells that express ROR‐γt and differentiate to Th17‐cells via an autocrine loop of STAT3‐activating cytokines (preTh17). STAT3‐deficient AD‐HIES patients lack Th17‐ and Tfh17‐cells but retain preTh17‐ and Th1/17‐cells.
Giorgia Moschetti   +18 more
wiley   +1 more source

EXACERBATED ECZEMA: ROLE OF BUILT ENVIRONMENT IN INCREASING DISEASE SEVERITY AMONG PAKISTANI PATIENTS

open access: yesPakistan Journal of Medicine and Dentistry, 2019
Atopic Eczema is a non-contagious skin disease. This study was undertaken to determine the role of home environment allergens in aggravation of atopic eczema by using EASI (Eczema Area And Severity Index) and POEM (Patient Oriented Eczema Measure ...
Bisma Laeeque   +3 more
doaj  

The Evolution of Sesame Seed Allergy Over Time

open access: yesAllergy, EarlyView.
This study analyzes the natural history of sesame over time and the changes in biomarkers between sesame allergic and sesame sensitised but tolerant children. The period prevalence of sesame allergy increased from 0.5% between 12 and 36 m to 1.5% between 7 and 12 y children in the EAT‐On study with 10 children developing new sesame allergy. Sesame‐sIgE
Ru‐Xin Foong   +14 more
wiley   +1 more source

Maternal stress triggers early-life eczema through fetal mast cell programming

open access: yes
International audiencePrenatal stress (PS) is a repeated exposure to aversive situations during pregnancy, including high emotional strain, which is suspected to affect homeostatic systems in infants.
Bodinier, Marie   +27 more
core   +1 more source

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