Results 141 to 150 of about 139,943 (292)
Australasian Journal of Dermatology, EarlyView.
Madeleine Louise Kelly, Crystal Williams
wiley +1 more source
Serotonin Degradation and Lipid Metabolism Regulate Human Tc2 Cell Effector Functions
Human Tc2 cells exhibit a metabolically active phenotype characterized by enhanced glycolysis, mitochondrial respiration, and fatty acid uptake dependent on PPARγ. Alarmins strongly amplify IL‐5 and IL‐13 production in Tc2 cells, supporting a shared immunometabolic program across type 2 lymphocytes.
Sabrina de Souza Ferreira +13 more
wiley +1 more source
Development of Nummular Dermatitis Following Dupilumab Therapy Suggests a Th17‐Driven Mechanism
Australasian Journal of Dermatology, EarlyView.
Olga Pawlik, Michelle McRae
wiley +1 more source
ABSTRACT The skin is far from a passive shield; it functions as a dynamic “living barrier” whose structural and immunological integrity is paramount in preventing atopic dermatitis (AD) and the subsequent progression of the atopic march toward food allergy (FA).
Klaudia Ryczaj +4 more
wiley +1 more source
ABSTRACT Mucosal surfaces are sites of highly dynamic interactions among epithelial and immune cells, environmental exposures, particularly dietary inputs, and the diverse microbial communities and their metabolites. These elements continually influence each other to maintain homeostasis and ensure appropriate immune discrimination between pathogens ...
Clara Delaroque +5 more
wiley +1 more source
Microbiota Signatures in Early Life and Their Association With Food Allergy: A Systematic Review
ABSTRACT Food allergy (FA) is increasing worldwide, and early life may be a critical window for immune training. We systematically reviewed observational human studies linking early‐life microbiota (infant, maternal, environmental, or extraintestinal) profiled using culture‐based and/or culture‐independent methods (including sequencing‐based approaches)
Eduard Flores Ventura +7 more
wiley +1 more source
This study examines the current state of food allergy prevention guideline implementation worldwide, identifying key variables that may explain the observed global variation. Among 731 healthcare professionals across 80 countries, geography and clinical specialty independently drove allergenic food introduction practices, creating an 8.5‐month practice
Agnes Sze‐yin Leung +20 more
wiley +1 more source
A COMPARATIVE STUDY ON EFFECT OF ENDOGENOUS AND EXOGENOUS ECZEMA ON QUALITY OF LIFE
Objective: To compare the effect of endogenous and exogenous eczema on quality of life using Dermatology Life Quality Index. Study Design: Cross- sectional comparative study.
Najia Ahmed +6 more
doaj
Shotgun Metagenomics Reveals Skin Microbiome Composition and Function in Infant Atopic Disease
Deep shotgun metagenomics profiled > 1000 infant skin swabs in the VITALITY cohort. Distinct skin microbiome signatures separated AD alone from AD with allergic co‐occurrence. Early Staphylococcus enrichment preceded later AD with allergic co‐occurrence. FLG mutations and strain‐level analyses revealed host and microbial features linked to AD.
Zeyang Shen +135 more
wiley +1 more source

