Results 141 to 150 of about 139,943 (292)

Serotonin Degradation and Lipid Metabolism Regulate Human Tc2 Cell Effector Functions

open access: yesAllergy, EarlyView.
Human Tc2 cells exhibit a metabolically active phenotype characterized by enhanced glycolysis, mitochondrial respiration, and fatty acid uptake dependent on PPARγ. Alarmins strongly amplify IL‐5 and IL‐13 production in Tc2 cells, supporting a shared immunometabolic program across type 2 lymphocytes.
Sabrina de Souza Ferreira   +13 more
wiley   +1 more source

Emollient Formulations and Skin Barrier Practices in the Context of Eczema and Food Allergy Prevention

open access: yesAllergy, EarlyView.
ABSTRACT The skin is far from a passive shield; it functions as a dynamic “living barrier” whose structural and immunological integrity is paramount in preventing atopic dermatitis (AD) and the subsequent progression of the atopic march toward food allergy (FA).
Klaudia Ryczaj   +4 more
wiley   +1 more source

Eczema

open access: yesInternational Journal of Clinical Practice, 1955
openaire   +2 more sources

Diet–Microbiome–Immune Interactions at the Gut Mucosa in Food Allergy: Mechanisms, Gaps, and Therapeutic Implications

open access: yesAllergy, EarlyView.
ABSTRACT Mucosal surfaces are sites of highly dynamic interactions among epithelial and immune cells, environmental exposures, particularly dietary inputs, and the diverse microbial communities and their metabolites. These elements continually influence each other to maintain homeostasis and ensure appropriate immune discrimination between pathogens ...
Clara Delaroque   +5 more
wiley   +1 more source

Microbiota Signatures in Early Life and Their Association With Food Allergy: A Systematic Review

open access: yesAllergy, EarlyView.
ABSTRACT Food allergy (FA) is increasing worldwide, and early life may be a critical window for immune training. We systematically reviewed observational human studies linking early‐life microbiota (infant, maternal, environmental, or extraintestinal) profiled using culture‐based and/or culture‐independent methods (including sequencing‐based approaches)
Eduard Flores Ventura   +7 more
wiley   +1 more source

Global Variation in Timing of Allergenic Food Introduction for Food Allergy Prevention: An International Survey of Healthcare Professionals

open access: yesAllergy, EarlyView.
This study examines the current state of food allergy prevention guideline implementation worldwide, identifying key variables that may explain the observed global variation. Among 731 healthcare professionals across 80 countries, geography and clinical specialty independently drove allergenic food introduction practices, creating an 8.5‐month practice
Agnes Sze‐yin Leung   +20 more
wiley   +1 more source

A COMPARATIVE STUDY ON EFFECT OF ENDOGENOUS AND EXOGENOUS ECZEMA ON QUALITY OF LIFE

open access: yesPakistan Armed Forces Medical Journal, 2019
Objective: To compare the effect of endogenous and exogenous eczema on quality of life using Dermatology Life Quality Index. Study Design: Cross- sectional comparative study.
Najia Ahmed   +6 more
doaj  

Shotgun Metagenomics Reveals Skin Microbiome Composition and Function in Infant Atopic Disease

open access: yesAllergy, EarlyView.
Deep shotgun metagenomics profiled > 1000 infant skin swabs in the VITALITY cohort. Distinct skin microbiome signatures separated AD alone from AD with allergic co‐occurrence. Early Staphylococcus enrichment preceded later AD with allergic co‐occurrence. FLG mutations and strain‐level analyses revealed host and microbial features linked to AD.
Zeyang Shen   +135 more
wiley   +1 more source

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