AbstractAtopic dermatitis, commonly known as eczema, is a common chronic, relapsing skin disease characterized by pruritus, disrupted epidermal barrier function, and immunoglobulin E–mediated sensitization to food and environmental allergens. Atopic dermatitis is a complex disease that arises from interactions between genes and the environment. Loci on
Andrew, Sohn +3 more
core +6 more sources
Professional Cleaners’ and Healthcare Workers’ Ability to Recognize Hand Eczema
Timely intervention reduces the risk of a poor prognosis in hand eczema, making early recognition of symptoms important in high-risk professions. However, limited data exist regarding the ability of cleaners and healthcare workers to recognize hand ...
Anna Glenn Ullum +3 more
doaj +2 more sources
Eczema/dermatitis belongs to the most pruritic of skin diseases. Pruritogenic mediators in the skin are still mostly unknown. Recent studies, however, have shown that the histamine 4 receptor plays an important role in itch pathophysiology; tryptase and IL-31 are also involved in atopic eczema itch.
Ulf, Darsow +4 more
openaire +3 more sources
The Rapid Eczema Trials’ Keep Control of Eczema Study: Specific advice on topical corticosteroid treatment duration for eczema flares versus usual care in adults and children. Protocol of an online, randomised controlled trial [version 1; peer review: 2 approved] [PDF]
Background A systematic review of international guidelines for eczema (syn. atopic dermatitis) highlighted variable recommendations for using topical corticosteroid (TCS), reflecting limited randomised controlled trial (RCT) evidence to inform practice ...
Paul Leighton +34 more
doaj +2 more sources
Background: Research has shown that eczema patients prefer some degree of shared control over treatment decisions, but little is known about factors perceived to be important to facilitate shared decision making (SDM).
Erin Foster, MD, PhD +3 more
doaj +1 more source
Hidden gems: a pilot project to solicit and reward patients’ and caregivers’ ideas for research
Background Patients and caregivers investigate a wide range of approaches to address the signs and symptoms of their condition. Such investigation could lead to new treatment insights or avenues for research.
Freya Moxham +3 more
doaj +1 more source
Factors related to eczema clinical trial participation among adult patients and caregivers
Background: Eczema can be difficult to treat due to its chronic, heterogeneous nature. Effective long-term treatments for adults and children are needed.
Jessica K. Johnson +3 more
doaj +1 more source
Hyperkeratotic hand eczema: Eczema or not? [PDF]
AbstractBackgroundHyperkeratotic hand eczema (HHE) is a typical clinical hand eczema subtype with a largely unknown pathophysiology.ObjectiveTo investigate histopathology, expression of keratins (K), epidermal barrier proteins, and adhesion molecules in HHE.MethodsPalmar skin biopsies (lesional and perilesional) were obtained from seven HHE patients ...
Klaziena Politiek +8 more
openaire +2 more sources
Burden of adult atopic dermatitis and unmet needs with existing therapies
Objective Patients with atopic dermatitis (AD) have low treatment satisfaction. In this study, we evaluated the humanistic burden, treatment satisfaction, and treatment expectations in patients with AD in the United States.
Elizabeth D. Bacci +6 more
doaj +1 more source
Factors Associated with Eczema Clinical Trial Awareness, Interest, and Participation in Adults
Despite the need for improved eczema therapies and a rapid increase in available eczema clinical trials, participation remains low. The aim of this study was to identify factors associated with clinical trial awareness, interest, and barriers to ...
Erin E. Grinich +6 more
doaj +1 more source

