Results 81 to 90 of about 129,126 (313)

Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis [PDF]

, 2014
Background: Atopic dermatitis (AD; eczema) is characterized by a widespread abnormality in cutaneous barrier function and propensity to inflammation. Filaggrin is a multifunctional protein and plays a key role in skin barrier formation.
Sherstnev, Alexander, O'Regan, Grainne M., Schurch, Nicholas J., Barton, Geoffrey J., Sandilands, Aileen, Irvine, Alan D., Brown, Sara J., Kroboth, Karin, Cole, Christian, Cole, Christian; id_orcid, Watson, Rosemarie M., Barton, Geoffrey J.; id_orcid, McLean, W. H. Irwin, Irwin McLean, W.H.   +13 more
core   +1 more source

The Role of Artificial Intelligence in Modern Allergology: A Review of Applications in Diagnosis, Prediction, and Management

JEADV Clinical Practice, EarlyView.
ABSTRACT Artificial Intelligence is rapidly transforming allergology by enhancing diagnosis, risk prediction, automation, patient communication, education, and therapy development. Machine learning approaches, including convolutional neural networks, recurrent architectures, and transformer‐based models, enable analysis of complex datasets from ...
Sebastian Seurig, Stephan Traidl, Sonja Mathes   +2 more
wiley   +1 more source

Managing Skin Diseases During Pregnancy: Treatment Discontinuation, Concerns and Physician Counselling

JEADV Clinical Practice, EarlyView.
Physiological changes during pregnancy can trigger or worsen dermatological conditions, yet evidence‐based guidance for safe management remains limited. In a cross‐sectional survey of 273 pregnant women, 33.7% reported having a skin disease, and 56% experienced worsening of symptoms.
Frederikke Seeberg, Anne Sofie Frølunde, Mette Deleuran, Line Kolding, Christian Vestergaard   +4 more
wiley   +1 more source

Prevalence of Colonization, Association With Disease Stage and Effect of Eradication of Staphylococcus aureus in Cutaneous T‐Cell Lymphoma: A Systematic Review and Meta‐Analysis

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Cutaneous T‐cell lymphoma (CTCL) is a rare and heterogeneous group of skin‐homing lymphomas with a largely unknown pathogenesis. Staphylococcus aureus (S. aureus) colonization has been implicated in exacerbating CTCL, particularly in advanced stages. Objectives This study assessed the prevalence of S.
Ida Lind Holm, Sarah Søltoft Rasmussen, Somaia Naassan, Misbah N. Ghazanfar, Kenneth Thomsen, Rikke Bech, Lise M. Lindahl, Maria Kamstrup, Simon Francis Thomsen, Zarqa Ali   +9 more
wiley   +1 more source

Whole exome sequencing detects novel variants in Saudi children diagnosed with eczema

Journal of Infection and Public Health, 2020
Background: Eczema is also known as atopic dermatitis is well-known for the skin disease globally. In Saudi Arabia, exome sequencing studies have not been documented.
Neda M. Bogari, Amr A. Amin, Husni H. Rayes, Ahmed Abdelmotelb, Faisal A. Al-Allaf, Anas Dannoun, Hiba S. Al-Amodi, Anas A. Sedayo, Hilal Almalk, Amna Moulana, Rania Balkhair, Fatma Jambi, Fakhriah Madani, Mwafaq Abutalib, Mohiuddin M. Taher, Abdellatif Bouazzaoui, Ashwag Aljohani, Mustafa N. Bogari, Udaya Raja G.K., Ahmed Fawzy, Khalid Khalaf Alharbi, Imran Ali Khan   +21 more
doaj   +1 more source

Startups Driving Artificial Intelligence Into Clinical Dermatology

JEADV Clinical Practice, EarlyView.
ABSTRACT Artificial intelligence (AI) is rapidly transitioning from innovation to routine clinical application in dermatology. This review examines how AI‐enabled technologies are being developed and integrated across diverse clinical purposes and workflows.
Dominique Du Crest, Benjamin Miguel Monteagudo, Stanislas Vandier, Mullarkey Dan, Svedenhag Per, Jon Friis, Monisha Madhumita, Lilit Garibyan, Tu‐Anh Duong, Merete Haedersdal, Vinzent Kevin Ortner   +10 more
wiley   +1 more source

Refractory Eczema as a Presenting Feature of Common Variable Immunodeficiency

JEADV Clinical Practice, EarlyView.
ABSTRACT Common variable immunodeficiency (CVID) is the most prevalent symptomatic inborn error of immunity (IEI) in adults. It presents with recurrent infections and non‐infectious complications, including autoimmunity, lymphoproliferation and dermatitis.
Mercedes Sanchez‐Diaz, Lars Matthies, Andrea Vanegas Ramirez   +2 more
wiley   +1 more source

Professional Cleaners’ and Healthcare Workers’ Ability to Recognize Hand Eczema

Acta Dermato-Venereologica
Timely intervention reduces the risk of a poor prognosis in hand eczema, making early recognition of symptoms important in high-risk professions. However, limited data exist regarding the ability of cleaners and healthcare workers to recognize hand ...
Anna Glenn Ullum, Farnam Barati Sedeh, Gregor B.E. Jemec, Kristina Sophie Ibler   +3 more
doaj   +1 more source

Gut Microbiota: A Reservoir for Extraintestinal Bacterial Infections in Febrile Term Infants

iLABMED, EarlyView.
Ran Wang, Renqiang Yu
wiley   +1 more source

Characteristics of Sensitive Scalp in French Women and Comparison With Scalp Dermatoses

JEADV Clinical Practice, EarlyView.
ABSTRACT Background A sensitive scalp is a particular location of sensitive skin, characterised by the occurrence of unpleasant sensations which cannot be explained by a skin disease. It is a common syndrome that could affect 30%–50% of women. Clinical data are scarce, and the impact on the quality of life poorly described.
Ficheux Anne‐Sophie, Melessike Kristel, Misery Laurent, Brenaut Emilie   +3 more
wiley   +1 more source