Results 41 to 50 of about 1,395,528 (162)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Classical Physics of Thermal Scalar Radiation in Two Spacetime Dimensions

, 2010
Thermal scalar radiation in two spacetime dimensions is treated within relativistic classical physics. Part I involves an inertial frame where are given the analogues both of Boltzmann's derivation of the Stefan-Boltzmann law and also Wien's derivation ...
Boyer, Timothy H.
core   +1 more source

Rotating saddle trap as Foucault's pendulum [PDF]

, 2015
One of the many surprising results found in the mechanics of rotating systems is the stabilization of a particle in a rapidly rotating planar saddle potential. Besides the counterintuitive stabilization, an unexpected precessional motion is observed.
Brouwer L. E. J., Brouwer L. E. J., Gascheau M., Kapitsa P. L., Landau L. D., Mark Levi, Neimark J. I., Oleg N. Kirillov   +7 more
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The relativistic Sagnac Effect: two derivations

, 2003
The phase shift due to the Sagnac Effect, for relativistic matter and electromagnetic beams, counter-propagating in a rotating interferometer, is deduced using two different approaches.
A Einstein, A Peres, A Tartaglia, A Tartaglia, AA Michelson, AA Michelson, B Mashhoon, C Cattaneo, C Cattaneo, C Cattaneo, C Cattaneo, C Cattaneo, C Møller, CW Misner, D Bini, D Diecks, E Mach, EJ Post, F Goy, F Harres, F Hasselbach, F Selleri, F Selleri, F. Riehle, FW Hehl, G Berkeley, G Grøn, G Papini, G Rizzi, G Rizzi, GB Malykin, GE Stedman, J Anandan, J Croca, J Stachel, J.J. Sakurai, JE Zimmermann, JP Vigier, M Born, M.L. Ruggiero, MG Sagnac, MG Sagnac, N Ashby, N Rosen, OJ Lodge, OJ Lodge, P Ehrenfest, P Harzer, P Tourrenc, P.K. Anastasowksi, R Anderson, R Arnowitt, R Schlegel, RD Klauber, RD Klauber, RH Boyer, S Bergia, S.A. Werner, TA Weber, V Vali, W Pauli, Y Aharonov, Zel’manov   +62 more
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Comment on "Classical and Quantum Interaction of the Dipole" [PDF]

, 2006
In this paper I have presented Comment on Anandan's paper (J. Anandan, Phys. Rev. Lett. 85, 1354 (2000)) [hep-th/9910018].Comment: 1 page, revtex; small changes, mainly typos, according to the published version in Phys.
J. D. Jackson, Tomislav Ivezić
core   +3 more sources

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source