Results 211 to 220 of about 29,853 (352)

C‐Terminal Nucleobase Modification Amplifies Peptide‐Mediated Liposome Fusion

open access: yesChemistry – A European Journal, EarlyView.
Let's come together right now. Cationic peptides are known to promote aggregation of negatively charged liposomes through electrostatic interaction. The process is reversible: once neutrality is achieved, liposomes disaggregate. Here, we demonstrate that end‐capping peptides with nucleobases turns the process into irreversible fusion.
Laura Morbiato   +4 more
wiley   +1 more source

A Review of Biomonitoring for Atrazine and Atrazine Metabolites Using Blood, Urine, and Sweat-Based Assays. [PDF]

open access: yesInt J Environ Res Public Health
Zielke C   +17 more
europepmc   +1 more source

Bayesian Optimization of Solvent‐Free Thermal Amidation via Reactive Extrusion

open access: yesChemistry – A European Journal, EarlyView.
Thermal amidation between a carboxylic acid and an amine was successfully conducted in an extruder in the absence of solvent, coupling agent, or catalyst, relying on an adapted Bayesian Optimization protocol. Active pharmaceutical ingredient moclobemide was synthesized on a larger scale, achieving excellent yield and low Process Mass Intensity (PMI ...
Matthieu Lavayssiere   +2 more
wiley   +1 more source

Design of Fuel‐Dependent, Complex‐Coacervate‐Based Synthetic Cells

open access: yesChemistry – A European Journal, EarlyView.
Fuel‐dependent synthetic cells form and persist only in the presence of chemical fuel, decaying under starvation. We establish design rules for hexapeptide‐based coacervates, showing that tryptophan enhances polyanion binding, extends lifetime, and reduces waste sensitivity.
Anna‐Lena Holtmannspötter   +9 more
wiley   +1 more source

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