Results 271 to 280 of about 29,853 (352)

Chinese Registry on Transjugular Intrahepatic Portosystemic Shunts (CN‐TIPS): Protocol for a Registry‐Based, Prospective Prognostic Study

Portal Hypertension &Cirrhosis, EarlyView.
CN‐TIPS is a nationwide, multicenter prospective registry that will enroll 10,000 adults with portal hypertension undergoing transjugular intrahepatic portosystemic shunt in China, integrating perioperative clinical and hemodynamic metrics with standardized imaging (including computational modeling in a dedicated subcohort) and multi‐omics biospecimens,
Yi Xiang, Yong Lv, Hongwei Zhou, Jianbo Zhao, Meng Niu, Jiacheng Liu, Guangchuan Wang, Qi Zhang, Weizhong Zhou, Beijia Yu, Jun Chi, Guo Han, Jiawei Zhang, Long Gao, Wenjing Liu, Zhang Zhang, Tianyu Liu, Wuhua Guo, He Zhao, Gao‐Jun Teng, Xiaolong Qi   +20 more
wiley   +1 more source

Exploring the impact of endocrine-disrupting chemicals on erectile dysfunction through network toxicology and machine learning. [PDF]

BMC Pharmacol Toxicol
Liu Z, Wang J, Li Y, Zeng Y, Wu Q, Zhu X, Zhou T, Deng Q.   +7 more
europepmc   +1 more source

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

Journal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá, Ladislav Androvič, Marcela Filipová, Michal Pechar, Richard Laga   +4 more
wiley   +1 more source

Field cancerization, accelerated aging, and immunosuppression: the rapid rise of hormone-sensitive and early-onset breast cancer. [PDF]

NPJ Breast Cancer
Parrish M, Traugh N, Seraj M, Kuperwasser C.   +3 more
europepmc   +1 more source

An Inimer Approach Based on Photo Iniferter RAFT Polymerization Toward One‐Pot Bottlebrush Copolymers Featuring Grafts From Less Activated Monomers

Journal of Polymer Science, EarlyView.
We present a stepwise one‐pot synthesis of bottlebrush copolymers using the inimer approach for less activated monomers (LAMs). Under the irradiation of wavelength 1 (λ1), an acrylamide‐based inimer was polymerized to create a backbone with active sites for grafting.
Lucía Diez‐Caballero, Tom Fielitz, Nora Unceta, Ramón J. Barrio, Matthias Hartlieb, Alberto Gómez‐Caballero   +5 more
wiley   +1 more source

Endocrine Disrupting Chemicals in Human Milk: A Systematic Review of Concentrations and Potential Health Implications. [PDF]

Curr Environ Health Rep
Dunn F, Sullivan H, Romano M, Chambers CD, Braun JM, Manz KE.   +5 more
europepmc   +1 more source

The Age and Origin of Block Deposits in the Victorian Alps, Australia

Permafrost and Periglacial Processes, EarlyView.
ABSTRACT Large periglacial block deposits are found in the mountains of southeastern Australia. Despite their widespread distribution, their mode of formation and age are poorly understood. These landforms hold considerable potential to shed light on the nature of cooling during glacial periods. In this paper we present a new study of block deposits in
Timothy T. Barrows, Michelle S. Worland, Julian Murton, Stephanie C. Mills, L. Keith Fifield   +4 more
wiley   +1 more source

Ecological and reproductive consequences of endocrine-disrupting chemicals in agricultural systems. [PDF]

Reprod Fertil
Payne W, Pool KR.
europepmc   +1 more source

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said, Job R. Schippers, Leila Atmowihardjo, Yingxue Li, Mick S. van der Plas, Harm J. Bogaard, Lieuwe D. J. Bos, Ron A. A. Mathôt, Jurjan Aman, Eleonora L. Swart, Imke H. Bartelink   +10 more
wiley   +1 more source