Results 41 to 50 of about 82,191 (303)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Investigation of Torque Enhancement in PMSMs for LEV Propulsion Using Magnet Segmentation

Energies
In this paper, the effect of eddy-current losses of permanent magnets (PMs) is studied by conducting analyses and experiments. PM segmentation is used to reduce eddy-current losses.
Ali Sinan Cabuk, Ozgur Ustun
doaj   +1 more source

Computationally Efficient Strand Eddy Current Loss Calculation in Electric Machines [PDF]

, 2019
A fast finite element (FE) based method for the calculation of eddy current losses in the stator windings of randomly wound electric machines is presented in this paper.
Chong, Yew Chuan, Demerdash, Nabeel, Fatemi, Alireza, Ionel, Dan M., Staton, Dave A., Wrobel, Rafal   +5 more
core   +1 more source

Association of Corticospinal Tract Asymmetry With Ambulatory Ability After Intracerebral Hemorrhage

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ambulatory ability after intracerebral hemorrhage (ICH) is important to patients. We tested whether asymmetry between ipsi‐ and contra‐lesional corticospinal tracts (CSTs) assessed by diffusion tensor imaging (DTI) is associated with post‐ICH ambulation.
Yasmin N. Aziz, Carl D. Langefeld, Mary E. Comeau, Miranda C. Marion, Tyler P. Behymer, Lee A. Gilkerson, Padmini Sekar, Weihong Yuan, Vivek Khandwala, Brady J. Williamson, Thomas Maloney, Achala Vagal, Pierce Boyne, Kari Dunning, Matthew L. Flaherty, Steven J. Kittner, Prachi Mehndiratta, Gunjan Y. Parikh, Michael L. James, David Roh, Fernando D. Testai, Farhaan S. Vahidy, James Thornton, Ranjit Bagga, Daniel Woo, Stacie L. Demel   +25 more
wiley   +1 more source

Computation of Losses in HTS Under the Action of Varying Magnetic Fields and Currents

, 2013
Numerical modeling of superconductors is widely recognized as a powerful tool for interpreting experimental results, understanding physical mechanisms and predicting the performance of high-temperature superconductor (HTS) tapes, wires and devices.
Grilli, Francesco, Gömöry, Fedor, Nguyen, Doan N., Pardo, Enric, Stenvall, Antti, Yuan, Weijia   +5 more
core   +1 more source

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim, Han Gil Seo, Roh‐Eul Yoo, Byung‐Mo Oh   +3 more
wiley   +1 more source

Study of Rotor Slot Wedge Eddy Current Loss of Nuclear Power Turbo-generator under Negative Sequence Operation

Journal of Harbin University of Science and Technology, 2018
In order to study the generator rotor slot wedge eddy current loss under different conditions . The 1407MVA turbo generator at half speed is researched as an example. Mathematical model is established in 2D electromagnetic field.
GE Bao-jun, ZHOU Jia-ju, WANG Li-kun, TAO Da-jun, LI Meng-qiao, HAN Ji-chao   +5 more
doaj   +1 more source

Practical Wide Frequency Approach for Calculating Eddy Current Losses in Transformer Windings [PDF]

, 2006
C
BARUDOV, S, Van den Bossche, Alex, VENCISLAV, V   +2 more
core   +2 more sources

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Research on Transient Electromagnetic Field and Eddy Current Losses Reduction in End of Large-Capacity Synchronous Condenser During UHVDC System Faults

IEEE Access
During the fault process of the ultra-high voltage direct current (UHVDC) system, the winding of the large-capacity synchronous condenser (SC) generates strong impulse current, leading to excessive eddy current losses and easily causing local overheating
Erhang Zhu, Yanping Liang, Lulu He
doaj   +1 more source