Results 161 to 170 of about 88,049 (302)

SmartDetectAI: An AI‐Powered Web App for Real‐Time Colorimetric Detection of Heavy Metals in Water

open access: yesAdvanced Intelligent Systems, EarlyView.
SmartDetectAI integrates silver nanoparticle‐based colorimetric sensing with an AI‐powered web app for rapid, on‐site detection of toxic heavy metals in water. By combining aggregation‐driven optical changes with machine learning analysis of red ‐ green ‐ blue values, the platform achieves portable, low‐cost, and accurate monitoring of Hg‐ and Cd‐based
Nishat Tasnim   +9 more
wiley   +1 more source

Neuromorphic Photonic Processing and Memory With Spiking Resonant Tunneling Diode Neurons and Neural Networks

open access: yesAdvanced Intelligent Systems, EarlyView.
This work shows resonant tunneling diode‐based opto‐electronic spiking neurons enabling fast edge detection in time series, a two‐layer photonic spiking neural network for complex classification, and a depth‐tunable photonic spiking memory system. Neuromorphic computing—modeled after the functionality and efficiency of biological neural systems—offers ...
Dafydd Owen‐Newns   +8 more
wiley   +1 more source

Microfluidic Mixing with the Dynamic Control of Magnetic Actuation

open access: yesAdvanced Intelligent Systems, EarlyView.
Schematic illustration and flow field visualization of magnetically actuated L‐shaped microrobots displaying cooperative vortex generation for enhanced microscale mixing. The left side shows the electromagnetic actuation setup, which enables programmable control of rotational direction and frequency.
Prashant Kishor Sharma   +2 more
wiley   +1 more source

Silicosis, Sarcoidosis, and Silicosarcoidosis Are Overlapping Diagnoses and Difficult to Differentiate

open access: yesAmerican Journal of Industrial Medicine, EarlyView.
ABSTRACT We evaluated 12 workers with documented exposure to respirable crystalline silica who were referred to a tertiary care center due to clinical suspicion of silicosis, sarcoidosis, or silicosarcoidosis. Although silica exposure is a well‐established risk factor for silicosis and has been associated with autoimmune diseases, mycobacterial ...
Guilherme Ward Leite   +9 more
wiley   +1 more source

Are There Causal Associations Between Obsessive‐Compulsive Disorder and Cardiometabolic Phenotypes? A Genetic Correlation and Bi‐Directional Mendelian Randomization Study

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT In epidemiological studies, obsessive‐compulsive disorder (OCD) is robustly associated with increased risk of cardiometabolic disorders, including cardiovascular diseases, type 2 diabetes, and obesity. However, the mechanisms behind these associations are unclear. We conducted genetic correlation analyses to explore shared genetic etiology and
Robyn E. Wootton   +217 more
wiley   +1 more source

Bioinformatics‐based discovery of the involvement of PSAT1 in mediating the anti‐lung adenocarcinoma activity of triptolide

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Transcriptome sequencing was performed on tumor tissues from triptolide‐treated tumor‐bearing mice. The sequencing results were integrated with data from public databases for comprehensive analysis, and potential regulatory targets of triptolide were identified.
Zhiwen Cao   +12 more
wiley   +1 more source

Anatomical Associations Between Focal Mitochondrial Metabolism and Patterns of Neurodegeneration in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Neurology, EarlyView.
Objective Amyotrophic lateral sclerosis (ALS) has a very specific neuroimaging signature, but the molecular underpinnings of the strikingly selective anatomic involvement have not elucidated to date. Accordingly, a large neuroimaging study was conducted with 258 participants to evaluate associations between patterns of neurodegeneration and focal ...
Marlene Tahedl   +10 more
wiley   +1 more source

Electronic Health Records to Test Multimorbidity Influences to Plasma Biomarker Interpretation for Alzheimer's Disease

open access: yesAnnals of Neurology, EarlyView.
Objective Plasma biomarkers of Alzheimer's disease (AD) pathology are frequently tested in specialized research settings, which limits the generalizability of findings. Using electronic health records and banked plasma, we evaluated plasma biomarkers—phosphorylated tau 217 (p‐tau217), β‐amyloid 1–42/1–40 (Aβ42/Aβ40) and p‐tau217/Aβ42—in a real‐world ...
Katheryn A.Q. Cousins   +12 more
wiley   +1 more source

Targeting the Membrane‐Embedded Rhomboid Protease GlpG: A Multimodal Strategy for Inhibitor Discovery and Mechanistic Insight

open access: yesAngewandte Chemie, EarlyView.
Created in BioRender. Bohg, C. (2026) https://BioRender.Com/ vi9hi4f. Rhomboid proteases are a mechanistically unique and evolutionarily conserved protein family. Despite their pharmacological relevance, the development of selective inhibitors has lagged behind that of soluble proteases.
Claudia Bohg   +21 more
wiley   +2 more sources

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