Results 211 to 220 of about 1,170,924 (343)
USP30 deubiquitinates and stabilizes MAT2A, thereby regulating DNA methylation and miRNA expression, which ultimately leads to disruption of lung endothelial barrier and inflammation. Abstract Microvascular dysfunction is a key contributor to the development of acute inflammatory diseases, characterized by heightened vascular hyperpermeability and ...
Baoyinna Baoyinna +11 more
wiley +1 more source
Tocilizumab as a treatment tool for ROSAH syndrome: a case report. [PDF]
Teixeira-Martins R +6 more
europepmc +1 more source
Using an affinity‐based probe, this study reveals that aristolochic acid directly binds to HIGD1A with high affinity in the kidney. This binding disrupts the HIGD1A‐TFAM interaction, which in turn triggers TFAM degradation, cytosolic mitochondrial DNA release, and the activation of inflammatory pathways. Abstract Exposure to aristolochic acids (AA) via
Yin Gong +15 more
wiley +1 more source
Limb volumetry using an iPad-Based three-dimensional scanner for the assessment of edema. [PDF]
Gao C, Liu F.
europepmc +1 more source
Hyperadrenocorticism of calorie restriction contributes to its anti‐inflammatory action in mice [PDF]
Allen, Brian D +6 more
core +2 more sources
Microglial lipid metabolic dysfunction drives neurodegeneration in glaucoma. We found loss of LRP1 causes lipid accumulation and inflammation. We developed alpinetin‐loaded nanoparticles (AlpNPs) that bind LRP1, activate the PPARγ‐LXRα‐ABCA1 pathway to restore lipid homeostasis, promote an anti‐inflammatory phenotype, and protect retinal ganglion cells,
Miao Wei +8 more
wiley +1 more source
A case of acute pulmonary edema in scrub typhus: a rare complication with normal cardiac and renal function. [PDF]
Sivagurunathan K +2 more
europepmc +1 more source
Magnetically‐Induced Suppression of Oxidative Stress Prevents Venous Thrombosis
Venous thromboembolism (VTE) remains a leading cause of cardiovascular mortality. This study demonstrates that static magnetic fields (SMF) offer a novel non‐pharmacological intervention against VTE by mitigating endothelial oxidative stress. Mechanistically, SMF elevates intracellular Ca2+, boosts ATP production, and suppresses NOX4‐mediated ROS ...
Nana Zhang +12 more
wiley +1 more source
Editorial: Mechanisms, Measurement, and Management of Vasogenic Edema After Stroke
Gabriel Broocks +3 more
doaj +1 more source

