Recombinant rSF toxoid enhances efficacy of bacterin-inactivated vaccine against F18+ Escherichia coli-induced edema disease in swine [PDF]
Background Edema disease (ED) and post-weaning diarrhea (PWD) are major health and economic challenges in the swine industry, primarily caused by F18+ Shiga toxin-producing Escherichia coli (STEC).
Yuqing Liu +6 more
doaj +6 more sources
Phenotypic and genotypic profiling of swine-derived Shiga toxin-producing Escherichia coli over a decade in South Korea: a framework for edema disease vaccine candidate strains selection [PDF]
IntroductionShiga toxin-producing Escherichia coli (STEC), particularly strains harboring Stx2e, are the primary cause of edema disease (ED) in swine, leading to acute mortality and economic loss. Despite the use of antimicrobials and autogenous vaccines,
Gyeong-Seo Park +17 more
doaj +5 more sources
Different ideas on the pathogenesis and treatment of swine edema-disease
Although literature data associate the reason of swine edema-disease with certain serotypes of Escherichia coli bacteria, the authors assume that the primary cause of edema is more different.
Gabriella Novotniné Dankó +1 more
semanticscholar +4 more sources
To simplify the diagnosis of swine edema disease, overnight culture supernatants of swine clinical samples were assayed using immunochromatographic test strips we developed previously.
H. Arimitsu +3 more
semanticscholar +5 more sources
An enzymatic mutant of Shiga-like toxin II variant is a vaccine candidate for edema disease of swine [PDF]
Edema disease (ED) of weanling pigs is caused by an infection with Escherichia coli that produces Shiga-like toxin II variant (SLT-IIv). Pathology identical to that caused by ED can be duplicated in pigs that are injected with less than 10 ng of purified SLT-IIv per kg of body weight.
V M Gordon +4 more
semanticscholar +4 more sources
Protective efficacy of a genetic subunit bacterin against edema disease of swine in mice.
The exotoxin SLT-IIeB from the Escherichia coli Ee strain was expressed in E. coli, and the recombinant protein was purified, mixed with the Ee strain, then emulsified with oil-emulsion adjuvants to obtain a mixed subunit bacterin. Groups of Kunming mice were immunized at weeks 0 and 2, and challenged intraperitoneally with the Ee strain at week 4 ...
X. Yang +7 more
semanticscholar +4 more sources
Cloning and sequencing of a Shiga-like toxin type II variant from Escherichia coli strain responsible for edema disease of swine [PDF]
A Shiga-like toxin type II variant (SLT-IIv) is produced by strains of Escherichia coli responsible for edema disease of swine and is antigenically related to Shiga-like toxin type II (SLT-II) of enterohemorrhagic E. coli. However, SLT-IIv is only active against Vero cells, whereas SLT-II is active against both Vero and HeLa cells. The structural genes
D. Weinstein +4 more
semanticscholar +5 more sources
Virulence plasmids in edema disease: Insights from whole-genome analysis of porcine O139:H1 Shiga toxin-producing Escherichia coli (STEC) strains [PDF]
This study investigates the plasmid sequences of porcine O139:H1 Shiga toxin-producing Escherichia coli (STEC) responsible for Edema Disease (ED). Whole-genome analysis reveals significant similarities between these strains and known plasmids, notably ...
Ali Nemati +4 more
doaj +3 more sources
Edema disease of swine: differentiation of clinical variants and terminal pathologies [PDF]
L. M. Liakhovych
semanticscholar +3 more sources
Cross-sectional survey of risk factors for edema disease Escherichia coli (EDEC) on commercial pig farms in Germany [PDF]
Background Edema disease (ED) in swine, usually caused by certain Shiga toxin-producing Escherichia coli (EDEC) in the first few weeks after weaning, has a high mortality rate in affected piglets and can lead to high economic losses in rearing.
Pia I. Berger +7 more
doaj +3 more sources

