Implantable drug delivery system: Frontiers of medicine‐engineering interdisciplinary
Interdisciplinary Medicine, Volume 4, Issue 4, July 2026.This review systematically summarizes the driving mechanisms of implantable on‐demand drug delivery systems (IDDS), including endogenous, exogenous, and closed‐loop strategies. It highlights the pivotal roles of flexible electronics and miniaturization in enhancing the tissue conformity and spatial adaptability.
Yu Zeng +9 more
wiley +1 more source
Indications and outcome of intravitreal bevacizumab injection in a Community Eye Hospital, Nepal. [PDF]
BMC OphthalmolThakali S +3 more
europepmc +1 more source
Cellular Senescence and Aging: Mechanisms, Disease Convergence, and Therapeutic Frontiers
MedComm, Volume 7, Issue 7, July 2026.This schematic illustrates the hierarchical and interconnected nature of the primary molecular hallmarks of aging. The progression of aging is driven by a convergence of intrinsic molecular insults. Within the nucleus, genomic instability and telomere attrition trigger persistent DDR, accompanied by extensive epigenetic alterations.
Guowei Cai +10 more
wiley +1 more source
Sequential Intravitreal Corticosteroid Rescue Including Ozurdex After Anti-VEGF Failure in Bilateral Uveitic Cystoid Macular Edema With Asymmetric Relapse. [PDF]
CureusSimaku E, Nour Edien A, Popa M.
europepmc +1 more source
MedComm, Volume 7, Issue 7, July 2026.Targeted biological agents targeting VEGF, integrin, dopamine D2 receptor, ROCK, and BCL‐XL have entered the clinical trial phase and deserve particular attention. The treatment paradigm has shifted toward personalized and precision medicine, positioning optimized SML as a promising adjunctive therapy.
Xinying Hu +7 more
wiley +1 more source
Effects of the epiretinal membrane on the outcomes of intravitreal dexamethasone implantation for macular edema secondary to branch retinal vein occlusion. [PDF]
Arq Bras Oftalmol, 2023 Altintas AGK, Ilhan C.
europepmc +1 more source
Repeatability of SpotChecks contrast sensitivity test in macular disease
Optometry and Vision Science, Volume 103, Issue 7, July 2026.ABSTRACT Purpose SpotChecks is an accessible contrast sensitivity test with good repeatability in healthy adults. This study compared its intra‐visit repeatability with the near Pelli–Robson test in adults with macular disease. Methods One eye from 29 adults with macular disease (mean age 71 ± 13 years) underwent high‐contrast logMAR acuity and two ...
Katlyn B. Sprague +4 more
wiley +1 more source
Comment on: Efficacy and safety of posterior subtenon interferon alfa-2B injection in recurrent inflammatory macular edema. [PDF]
Indian J OphthalmolSahare H, Anupama H.
europepmc +1 more source
Integrated Population Pharmacokinetic Analysis of Intravitreal Aflibercept Drug Products
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 7, July 2026.ABSTRACT Neovascular age‐related macular degeneration (nAMD) and diabetic macular edema (DME) can cause substantial vision loss. The 2‐mg drug product of aflibercept (AFL‐2)—an anti‐vascular endothelial growth factor agent—has established efficacy and safety in both diseases.
Sébastien Bihorel +10 more
wiley +1 more source