Results 211 to 220 of about 90,240,046 (296)

Transcatheter Tricuspid Valve Annuloplasty vs Edge-to-Edge Repair: A Propensity-Matched Multicenter Comparative Analysis. [PDF]

JACC Adv
von Stein J, von Stein P, Stolz L, Althoff J, Hasse C, Rosch S, Rudolph F, Kirchner J, Goebel B, Koell B, Rottbauer W, Rassaf T, Beucher H, Kraus M, Kassar M, Geisler T, Rück A, Ferreira-Martins J, Toggweiler S, Sagmeister P, Westermann D, Stocker TJ, Weckbach LT, Näbauer M, Dawkins S, Kister T, Vorpahl M, Konstandin MH, Luedike P, Kessler M, Iliadis C, Lauten P, Besler C, Kalbacher D, Friedrichs K, Gerçek M, Granada JF, Lurz P, Hausleiter J, Wild MG, Körber MI, PASTE Investigators.   +41 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

The GLIDE Score: One-Year Outcomes Following Tricuspid Transcatheter Edge-to-Edge Repair. [PDF]

Struct Heart
Rudolph F, Narang A, Körber MI, Friedrichs KP, Kirchner J, Ivannikova M, Esperanca Clara Göttsche C, Althoff J, Cremer P, Luedike P, Rudolph TK, Geisler T, Kassar M, Potratz M, Rassaf T, Pfister R, Praz F, Rudolph V, Gerçek M, Davidson CJ.   +19 more
europepmc   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

Using Robotics to Improve Transcatheter Edge-to-Edge Repair of the Mitral Valve. [PDF]

IEEE Robot Autom Lett
Pistorius L, Nayar NU, Tran P, Elmariah S, Dupont PE.   +4 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Novel Transcatheter Edge-to-Edge Repair System for Degenerative Mitral Regurgitation: 1-Year Outcomes. [PDF]

JACC Asia
Zhu D, Fang Z, Liu X, Zhang N, Liu Y, Wang Y, Ma L, Liu J, Yang J, Li Y, Luo C, Peng X, Zhong W, Chen L, Xu J, Ouyang F, Xiu J, Liu J, He B, Chen M, Zhou S, Pan X.   +21 more
europepmc   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Successful Surgical Tricuspid Valve Repair of Severe Recurrent Tricuspid Regurgitation After Transcatheter Edge-to-Edge Repair. [PDF]

JACC Case Rep
Winkler A, Gansterer K, Boxhammer E, Neuner M, Kirnbauer M, Wuppinger T, Dinges C.   +6 more
europepmc   +1 more source

Effects of tricuspid transcatheter edge-to-edge repair on tricuspid annulus diameter - Data from the TriValve registry.

International Journal of Cardiology
G. Russo, R. Hahn, H. Alessandrini, M. Andreas, L. Badano, Daniel Braun, Kim A. Connelly, P. Denti, R. Estévez-Loureiro, N. Fam, M. Gavazzoni, J. Hausleiter, D. Himbert, D. Kalbacher, A. Latib, E. Lubos, Sebastian Ludwig, P. Lurz, V. Monivas, G. Nickenig, D. Pedicino, G. Pedrazzini, A. Pozzoli, F. Praz, J. Rodés-Cabau, K. Rommel, J. Schofer, H. Sievert, G. Tang, H. Thiele, M. Unterhuber, R. von Bardeleben, J. Webb, Stephan Windecker, Martin B. Leon, F. Maisano, M. Taramasso   +36 more
semanticscholar   +1 more source