Results 141 to 150 of about 1,425,497 (376)

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

open access: yesFEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo   +11 more
wiley   +1 more source

The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions

open access: yesFEBS Open Bio, EarlyView.
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh   +2 more
wiley   +1 more source

On harmonious coloring of hypergraphs [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science
A harmonious coloring of a $k$-uniform hypergraph $H$ is a vertex coloring such that no two vertices in the same edge have the same color, and each $k$-element subset of colors appears on at most one edge. The harmonious number $h(H)$ is the least number
Sebastian Czerwiński
doaj   +1 more source

Menthol‐like cooling compounds, including (R)‐(‐)‐carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K

open access: yesFEBS Open Bio, EarlyView.
We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Miyuu Saito, Takumi Misaka
wiley   +1 more source

Phosphomimetic mutations near active sites of proteins in Thermus thermophilus suggest a widespread regulatory mechanism

open access: yesFEBS Open Bio, EarlyView.
In Thermus thermophilus, more than half of the phosphorylation sites identified by proteomic analysis are located near the active site. All phosphomimetic mutants of phosphosites of six enzymes belonging to different families showed severely reduced activity compared with the wild‐type, particularly in the turnover number.
Anzu Nishiwaki   +3 more
wiley   +1 more source

Cartesian积与邻点可区别着色之间的关系(Relation between Cartesian product and adjacent vertex distinguishing coloring)

open access: yesZhejiang Daxue xuebao. Lixue ban, 2017
A proper k-edge coloring of a graph G is an assignment of k colors 1, 2, …, k to edges of G such that any two adjacent edges receive the different colors.
WANGGuoxing(王国兴)
doaj   +1 more source

Structural and functional characterization of chitinase from carnivorous plant Drosera adelae

open access: yesFEBS Open Bio, EarlyView.
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda   +7 more
wiley   +1 more source

Parsimonious edge-coloring on surfaces

open access: yesElectronic Journal of Graph Theory and Applications, 2018
We correct a small error in a 1996 paper of Albertson and Haas, and extend their lower bound for the fraction of properly colorable edges of planar subcubic graphs that are simple, connected, bridgeless, and edge-maximal to other surface embeddings of ...
Sarah-Marie Belcastro
doaj   +1 more source

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