Results 41 to 50 of about 91,208 (231)

Majority Edge-Colorings of Graphs

open access: yesThe Electronic Journal of Combinatorics, 2023
We propose the notion of a majority $k$-edge-coloring of a graph $G$, which is an edge-coloring of $G$ with $k$ colors such that, for every vertex $u$ of $G$, at most half the edges of $G$ incident with $u$ have the same color. We show the best possible results that every graph of minimum degree at least $2$ has a majority $4$-edge-coloring, and that ...
Bock, Felix   +5 more
openaire   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

The min-max edge q-coloring problem [PDF]

open access: yes, 2013
In this paper we introduce and study a new problem named \emph{min-max edge $q$-coloring} which is motivated by applications in wireless mesh networks. The input of the problem consists of an undirected graph and an integer $q$.
Larjomaa, Tommi, Popa, Alexandru
core  

On Partitioning the Edges of 1-Plane Graphs

open access: yes, 2016
A 1-plane graph is a graph embedded in the plane such that each edge is crossed at most once. A 1-plane graph is optimal if it has maximum edge density.
Lenhart, William J.   +2 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Solution of Vizing's Problem on Interchanges for Graphs with Maximum Degree 4 and Related Results [PDF]

open access: yes, 2014
Let $G$ be a Class 1 graph with maximum degree $4$ and let $t\geq 5$ be an integer. We show that any proper $t$-edge coloring of $G$ can be transformed to any proper $4$-edge coloring of $G$ using only transformations on $2$-colored subgraphs (so-called ...
Asratian, Armen S.   +1 more
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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